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听神经瘤的磁共振成像:35例患者的回顾

MRI in acoustic neuroma: a review of 35 patients.

作者信息

Curati W L, Graif M, Kingsley D P, King T, Scholtz C L, Steiner R E

出版信息

Neuroradiology. 1986;28(3):208-14. doi: 10.1007/BF00548194.

Abstract

This retrospective study is aimed to assess the diagnostic efficacy of MRI in relation to contrast enhanced CT and air-CT-cisternography. MRI examinations were performed in 35 patients with suspected neurosensorial damage and suggestive of acoustic neuroma: 27 presented on MRI with unilateral tumors, 3 patients had a bilateral tumor and 5 patients were negative on all imaging modalities. The total number of acoustic neuromas detected was therefore 33. To date microscopic analysis has been performed on 12 tumors and histological data based on type Antoni A and Antoni B classification is available. Contrast enhanced CT detected 19 tumors, yielding an overall sensitivity rate of 58%. Air-CT cisternography identified an additional 5 tumors with a sensitivity rate of 100%. MRI identified 33 acoustic neuromas in 30 patients and was negative in 5 patients (sensitivity and accuracy 100%). Considering sensitivity in relation to location, MRI was much better than contrast enhanced CT for internal auditory canal (IAC) tumors (100% versus 36%) and better for cerebello-pontine angle tumors (CPA) tumors (100% versus 68%). The evolution of MRI technique, the various pulse sequences used and their actual selection is discussed. Seven patients received a paramagnetic contrast agent (Gadolinium-DTPA) with the additional benefit of a better demonstration of the tumor. The results suggest that MRI is the best non invasive technique for demonstrating acoustic neuromas.

摘要

本回顾性研究旨在评估磁共振成像(MRI)相对于增强CT和气脑池造影CT的诊断效能。对35例疑似神经感觉损伤且提示听神经瘤的患者进行了MRI检查:27例MRI显示为单侧肿瘤,3例为双侧肿瘤,5例在所有成像方式下均为阴性。因此,检测到的听神经瘤总数为33个。迄今为止,已对12个肿瘤进行了显微镜分析,并获得了基于Antoni A和Antoni B分类的组织学数据。增强CT检测到19个肿瘤,总体灵敏度为58%。气脑池造影CT又发现了5个肿瘤,灵敏度为100%。MRI在30例患者中发现了33个听神经瘤,5例为阴性(灵敏度和准确率均为100%)。就位置而言,考虑灵敏度,MRI对内耳道(IAC)肿瘤的检测比增强CT好得多(100%对36%),对桥小脑角(CPA)肿瘤的检测也更好(100%对68%)。文中讨论了MRI技术的发展、所使用的各种脉冲序列及其实际选择。7例患者接受了顺磁性造影剂(钆喷酸葡胺),其额外好处是能更好地显示肿瘤。结果表明,MRI是显示听神经瘤的最佳无创技术。

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