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术后巴氏指数较高与老年髋部骨折术后一年死亡率较低相关:一项回顾性病例对照研究。

A Higher Postoperative Barthel Index at Discharge is Associated with a Lower One-Year Mortality After Hip Fracture Surgery for Geriatric Patients: A Retrospective Case‒Control Study.

机构信息

Department of Orthopedics, Peking University First Hospital, Beijing, 100034, People's Republic of China.

Department of Orthopedics, Peking University Third Hospital, Beijing, 100191, People's Republic of China.

出版信息

Clin Interv Aging. 2023 May 23;18:835-843. doi: 10.2147/CIA.S409282. eCollection 2023.

Abstract

PURPOSE

To evaluate the relationship between the postoperative Barthel index assessing activities of daily living at discharge and the one-year mortality after hip fracture surgery.

METHODS

Patients with hip fracture admitted to Peking University First Hospital from January 2015 to January 2020 were enrolled retrospectively according to the inclusion and exclusion criteria. The Barthel index and other related confounding variables were collected. Logistic regression and Kaplan‒Meier survival curves were constructed to explore the relationship between the postoperative Barthel index at discharge and the one-year mortality of geriatric patients after hip fracture surgery.

RESULTS

A total of 444 patients with a mean age of 81.61±6.14 years were included. A significant difference was not observed in the preoperative Barthel index at admission between the deceased group and the surviving group (38.90±15.83 vs 36.96±10.74, =0.446). However, the difference in the postoperative Barthel index at discharge between these two groups was statistically significant (43.08±14.40 vs 53.18±13.43, P<0.001). The multivariable logistic regression analysis revealed that the postoperative Barthel index at discharge was an independent risk factor for one-year mortality after adjustment for confounding variables (adjusted OR 0.73, 95% CI 0.55-0.98, p˂0.05). The Kaplan‒Meier survival curve showed that patients who had a high Barthel index (≥50) at discharge had a significantly lower mortality in the long term than patients with a low Barthel index (<50) at discharge (P< 0.001).

CONCLUSION

The postoperative Barthel index at discharge was independently associated with the one-year mortality of geriatric patients after hip fracture surgery. A higher postoperative Barthel index at discharge indicated a lower mortality after hip fracture surgery. The Barthel index at discharge has the potential to provide essential prognostic information for early risk stratification and directing future care.

摘要

目的

评估髋关节骨折术后出院时日常生活活动能力的巴氏指数(Barthel 指数)与术后 1 年死亡率之间的关系。

方法

回顾性纳入 2015 年 1 月至 2020 年 1 月期间北京大学第一医院收治的髋关节骨折患者,根据纳入和排除标准进行筛选。收集 Barthel 指数和其他相关混杂变量。构建逻辑回归和 Kaplan-Meier 生存曲线,以探讨髋关节骨折术后出院时的 Barthel 指数与老年患者术后 1 年死亡率之间的关系。

结果

共纳入 444 例患者,平均年龄为 81.61±6.14 岁。死亡组与存活组入院时的术前 Barthel 指数无显著差异(38.90±15.83 与 36.96±10.74,=0.446)。然而,两组出院时的术后 Barthel 指数差异具有统计学意义(43.08±14.40 与 53.18±13.43,P<0.001)。多变量逻辑回归分析显示,调整混杂因素后,出院时的 Barthel 指数是术后 1 年死亡率的独立危险因素(调整后 OR 0.73,95%CI 0.55-0.98,p˂0.05)。Kaplan-Meier 生存曲线显示,出院时 Barthel 指数较高(≥50)的患者在长期内的死亡率明显低于出院时 Barthel 指数较低(<50)的患者(P<0.001)。

结论

髋关节骨折术后出院时的 Barthel 指数与老年患者髋关节骨折术后 1 年死亡率独立相关。出院时 Barthel 指数较高提示髋关节骨折术后死亡率较低。Barthel 指数出院时有潜力为早期风险分层和指导未来护理提供重要预后信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bbf/10224694/1c54507a44a4/CIA-18-835-g0001.jpg

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