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日本鹿儿岛髋部骨折手术后死亡率及日常生活活动能力恶化的预测因素

Predictive factors of mortality and deterioration in performance of activities of daily living after hip fracture surgery in Kagoshima, Japan.

作者信息

Ishidou Yasuhiro, Koriyama Chihaya, Kakoi Hironori, Setoguchi Takao, Nagano Satoshi, Hirotsu Masataka, Yamamoto Takuya, Yokouchi Masahiro, Komiya Setsuro

机构信息

Department of Medical Joint Materials, Kagoshima University, Kagoshima, Japan.

Department of Epidemiology and Preventive Medicine, Kagoshima University, Kagoshima, Japan.

出版信息

Geriatr Gerontol Int. 2017 Mar;17(3):391-401. doi: 10.1111/ggi.12718. Epub 2016 Jan 28.

Abstract

AIM

Given that different hospitals achieve different outcomes, optimal evaluation of treatment outcomes in the local community requires evaluation of many institutions in that area. We carried out a prospective multicenter cohort study in Kagoshima Prefecture to identify factors that contribute to deterioration in activities of daily living performance and patient mortality 1 year after surgical treatment of hip fractures.

METHODS

We prospectively enrolled 387 patients who underwent surgery for hip fractures in 33 registered facilities within a 6-month period from February to July 2007. Logistic regression analysis was carried out to identify factors that contribute to deterioration in activities of daily living performance and death within 1 year after surgery.

RESULTS

An increased risk of Barthel Index (BI) deterioration was associated with increased age (P for trend = 0.003), worse pre-injury BI (P for trend = 0.021), trochanteric fractures (OR 2.07, 95% CI 1.31-3.27), worse BI at discharge (P for trend < 0.001) and postoperatively developed cognitive impairment (OR 6.34, 95% CI 2.15-18.7). The OR for BI deterioration in patients with newly-diagnosed disease after discharge was approximately 9.16 (95% CI 4.03-20.8). No factors except age and sex were statistically significant as the preoperative indicators of mortality risk. Only BI at discharge was a significant determinant of mortality risk (P for trend = 0.013) after adjusting for the effects of age and sex.

CONCLUSIONS

Patients with poor activities of daily living performance at the time of hospital discharge were likely to show poor functional recovery and a high 1-year postoperative mortality. Geriatr Gerontol Int 2017; 17: 391-401.

摘要

目的

鉴于不同医院的治疗结果存在差异,要对当地社区的治疗结果进行最佳评估,就需要对该地区的多个机构进行评估。我们在鹿儿岛县开展了一项前瞻性多中心队列研究,以确定导致髋部骨折手术治疗1年后日常生活活动能力下降和患者死亡的因素。

方法

我们前瞻性地纳入了2007年2月至7月这6个月期间在33家注册医疗机构接受髋部骨折手术的387例患者。进行逻辑回归分析,以确定导致术后1年内日常生活活动能力下降和死亡的因素。

结果

Barthel指数(BI)恶化风险增加与年龄增长(趋势P = 0.003)、伤前BI较差(趋势P = 0.021)、转子间骨折(比值比2.07,95%可信区间1.31 - 3.27)、出院时BI较差(趋势P < 0.001)以及术后出现认知障碍(比值比6.34,95%可信区间2.15 - 18.7)相关。出院后新诊断疾病患者BI恶化的比值比约为9.16(95%可信区间4.03 - 20.8)。除年龄和性别外,术前无其他因素作为死亡风险指标具有统计学意义。在调整年龄和性别的影响后,仅出院时的BI是死亡风险的显著决定因素(趋势P = 0.013)。

结论

出院时日常生活活动能力较差的患者术后功能恢复可能较差,术后1年死亡率较高。《老年医学与老年病学国际杂志》2017年;17: 391 - 401。

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