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药用植物用于防治淋巴丝虫病:现状与未来展望。

Use of medicinal plants as a remedy against lymphatic filariasis: Current status and future prospect.

作者信息

Fordjour Fatima A, Osei-Poku Priscilla, Genfi Afua K A, Ainooson Kwaw G, Amponsah Kingsley, Arthur Patrick K, Stephenson G Richard, Kwarteng Alexander

机构信息

Department of Microbiology University for Development Studies Tamale Ghana.

Department of Biochemistry and Biotechnology, College of Science Kwame Nkrumah University of Science and Technology Kumasi Ghana.

出版信息

Health Sci Rep. 2023 May 27;6(5):e1295. doi: 10.1002/hsr2.1295. eCollection 2023 May.

Abstract

Despite the successes achieved so far with the Global Programme to Eliminate Lymphatic Filariasis, there is still an appreciable number of lymphatic filarial patients who need alternative treatment and morbidity management strategies. The unresponsiveness of some cohorts to the drugs used in the mass drug administration program is currently raising a lot of questions and this needs urgent attention. Natural medicinal plants have a long-standing history of being effective against most disease conditions. Countries such as India have been able to integrate their natural plant remedies into the treatment of lymphatic filarial conditions, and the results are overwhelmingly positive. Components of , , and spp have been shown to have anti-inflammatory, anticancerous, and antimicrobial activities in animal models. Therefore, this review calls for attention toward the use of natural plant components as an alternate treatment against lymphatic filariasis to help reduce the World Health Organization's burden of providing drugs for people in need of treatment every year.

摘要

尽管全球消除淋巴丝虫病规划迄今已取得成功,但仍有相当数量的淋巴丝虫病患者需要替代治疗和发病管理策略。目前,一些群体对大规模药物管理计划中使用的药物无反应,这引发了诸多问题,亟待关注。天然药用植物长期以来一直对大多数疾病有效。像印度这样的国家已能够将其天然植物疗法纳入淋巴丝虫病的治疗中,且结果极为积极。在动物模型中,已证明、和属植物的成分具有抗炎、抗癌和抗菌活性。因此,本综述呼吁关注使用天然植物成分作为治疗淋巴丝虫病的替代方法,以帮助减轻世界卫生组织每年为有治疗需求的人提供药物的负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e310/10224507/4ef8ad56cb7f/HSR2-6-e1295-g001.jpg

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