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颈动脉窦神经C纤维从猫的颈动脉体释放儿茶酚胺。

Carotid sinus nerve C-fibers release catecholamines from the cat carotid body.

作者信息

Almaraz L, Fidone S

出版信息

Neurosci Lett. 1986 Jun 18;67(2):153-8. doi: 10.1016/0304-3940(86)90389-7.

DOI:10.1016/0304-3940(86)90389-7
PMID:3725209
Abstract

Previous studies have demonstrated that unmyelinated fibers in the cat carotid sinus nerve (CSN) are capable of inhibiting chemoreceptor activity from the carotid body. While the mechanism(s) underlying this phenomenon are unknown, it has been postulated that carotid body catecholamines may be involved in mediating this inhibitory effect. In this study, the in vitro cat carotid body-CSN preparation was used to investigate the effects of CSN stimulation on the release of [3H]catecholamines from the carotid body. The results showed that labeled catecholamines were released from this organ only when C-fibers were recruited by nerve stimulation.

摘要

以往的研究表明,猫颈动脉窦神经(CSN)中的无髓纤维能够抑制来自颈动脉体的化学感受器活动。虽然这种现象背后的机制尚不清楚,但据推测,颈动脉体儿茶酚胺可能参与介导这种抑制作用。在本研究中,采用体外猫颈动脉体 - CSN 制备方法来研究 CSN 刺激对颈动脉体释放 [3H] 儿茶酚胺的影响。结果表明,只有当神经刺激募集 C 纤维时,标记的儿茶酚胺才会从该器官释放。

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Neurosci Lett. 1986 Jun 18;67(2):153-8. doi: 10.1016/0304-3940(86)90389-7.
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Effects of almitrine on the release of catecholamines from the rabbit carotid body in vitro.烯丙哌三嗪对体外兔颈动脉体儿茶酚胺释放的影响。
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Ventilatory response to hyperoxia in newborn rats born in hypoxia--possible relationship to carotid body dopamine.
缺氧环境下出生的新生大鼠对高氧的通气反应——与颈动脉体多巴胺的可能关系
J Physiol. 1992 Oct;456:645-54. doi: 10.1113/jphysiol.1992.sp019358.