Wennergren M, Krantz M, Hjalmarson O, Karlsson K
Obstet Gynecol. 1986 Jul;68(1):49-53.
Etiologic and pathogenetic factors responsible for respiratory disturbances in full-term infants are still unclear. The authors' intention was to analyze to what extent fetal stress, expressed in terms of abnormal fetal heart rate pattern, was reflected in neonatal respiratory disturbance. The study was performed prospectively over one year and included 157 term infants. Contrary to general belief, there was a significantly lower incidence of respiratory disturbances after ominous fetal heart rate pattern, ie, basal bradycardia, late or severe variable decelerations, and reduced variability than after a normal fetal heart rate pattern. It is suggested that these results may be due to a favorable effect on the fetal lung of systemic or local factors, produced in response to intrauterine stress.
足月儿呼吸障碍的病因和发病机制仍不清楚。作者的目的是分析以异常胎儿心率模式表示的胎儿应激在多大程度上反映在新生儿呼吸障碍中。该研究前瞻性地进行了一年,纳入了157名足月儿。与一般看法相反,胎儿心率模式异常(即基础心动过缓、晚期或重度可变减速以及变异性降低)后呼吸障碍的发生率明显低于正常胎儿心率模式后。有人认为,这些结果可能是由于对子宫内应激产生的全身或局部因素对胎儿肺的有利影响。