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病例报告:眼部组织诊断先前未确诊的广泛耐药性肺结核。

Case Report: Ocular Tissue Diagnosis of Previously Undiagnosed, Extensively Drug-Resistant Pulmonary Tuberculosis.

机构信息

Uveitis Service, LV Prasad Eye Institute, Hyderabad, India.

The Cornea Institute, LV Prasad Eye Institute, Hyderabad, India.

出版信息

Am J Trop Med Hyg. 2023 May 30;109(1):57-59. doi: 10.4269/ajtmh.22-0769. Print 2023 Jul 5.

Abstract

We describe a patient with concurrent ocular and pulmonary tuberculosis (TB) in whom the diagnosis of extensively drug-resistant TB was made through phenotypic drug-sensitivity testing of an ocular fluid sample after sputum testing yielded incomplete results. Our results are remarkable, because culture-based diagnosis of TB in ocular fluid is unusual. We not only overcame this limitation, but also were able to create a complete drug-sensitivity testing profile from ocular samples, which led to effecting appropriate therapy for the patient.

摘要

我们描述了一例同时患有眼结核和肺结核(TB)的患者,在痰检结果不完整的情况下,通过对眼液样本进行表型药物敏感性测试,诊断为广泛耐药性 TB。我们的结果很显著,因为在眼液中进行基于培养的 TB 诊断并不常见。我们不仅克服了这一限制,还能够从眼液样本中创建完整的药物敏感性测试谱,从而为患者提供了适当的治疗。

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本文引用的文献

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Current tools available for the diagnosis of drug-resistant tuberculosis.目前可用于诊断耐多药结核病的工具。
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