评价 BD Phoenix CPO Detect Test 检测产碳青霉烯酶肠杆菌科细菌的效果。
Evaluation of the BD Phoenix CPO Detect Test for the detection of carbapenemase-producing Enterobacterales.
机构信息
Department of Medical Microbiology, Akdeniz University Faculty of Medicine, Antalya, Turkey.
Department of Infectious Diseases & Clinical Microbiology, Akdeniz University Faculty of Medicine, Antalya, Turkey.
出版信息
Future Microbiol. 2023 May;18:399-405. doi: 10.2217/fmb-2022-0071. Epub 2023 May 31.
This study aimed to evaluate the performance of the BD Phoenix CPO Detect Test (BD Diagnostic Systems) for the detection and classification of carbapenemase-mediated carbapenem resistance. A total of 447 Enterobacterales strains were included in the study. All strains were tested with the BD Phoenix CPO Detect Test and the modified carbapenem inactivation method. Carbapenemase production was detected in 157 of 159 carbapenemase producers, including 95.7% of class B and 99.2% of class D isolates using the BD Phoenix CPO Detect Test. BD Phoenix CPO Detect has a sensitivity of 98.7% and a specificity of 95.5% in detecting carbapenemase production. The classification of OXA-48 and class B carbapenemases, the most common carbapenemases circulating in Turkey, was highly accurate.
本研究旨在评估 BD Phoenix CPO Detect Test（BD 诊断系统）在检测和分类碳青霉烯酶介导的碳青霉烯耐药性方面的性能。共有 447 株肠杆菌科菌株纳入本研究。所有菌株均采用 BD Phoenix CPO Detect Test 和改良碳青霉烯失活法进行检测。BD Phoenix CPO Detect Test 检测到 159 株碳青霉烯酶产生菌中的 157 株产碳青霉烯酶，其中 95.7%的 B 类和 99.2%的 D 类分离株产碳青霉烯酶。BD Phoenix CPO Detect Test 检测产碳青霉烯酶的灵敏度为 98.7%，特异性为 95.5%。对在土耳其流行的最常见碳青霉烯酶 OXA-48 和 B 类碳青霉烯酶的分类具有很高的准确性。
Zotero 插件