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与后路脊柱融合术相比,前路椎体拴系术在青少年特发性脊柱侧凸中能否提供更好的活动度结果?一项系统评价。

Can anterior vertebral body tethering provide superior range of motion outcomes compared to posterior spinal fusion in adolescent idiopathic scoliosis? A systematic review.

作者信息

Wong Darren Li Liang, Mong Pak Tung, Ng Chun Yin, Ong Chun Kwan, Qian Zhekai, Shao Mang Hong, Sin Ling Kwan Ernest, Wong Bao Yi, Wong Chun Ming, Cheung Jason Pui Yin, To Michael

机构信息

Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, China.

出版信息

Eur Spine J. 2023 Sep;32(9):3058-3071. doi: 10.1007/s00586-023-07787-1. Epub 2023 May 31.

Abstract

PURPOSE

Anterior vertebral body tethering (AVBT) was introduced as a fusionless alternative to treating adolescent idiopathic scoliosis (AIS) while preserving range of motion (ROM). This is the first systematic review to compare the ROM outcomes between AVBT and PSF in treating AIS.

METHODS

We conducted a comprehensive search on PubMed, EMBASE, MEDLINE, and Cochrane Library. Inclusion criteria were patients with AIS treated with AVBT or PSF or both, and clearly defined ROM outcomes; exclusion criteria were scoliosis other than AIS, biomechanical or cadaveric studies, non-English publications, case reports, conference summaries, unpublished literature, commentaries, and reviews. Primary outcome was ROM. Secondary outcomes included Cobb angle correction, quality of life (QOL), complications, and muscle strength and endurance.

RESULTS

Twelve studies were included in this review. We found moderate evidence to support that AVBT results in superior ROM outcomes than PSF while achieving comparable Cobb angle correction with low evidence. The comparison of QOL outcomes between AVBT and PSF remained inconclusive. In addition to the complications noted conventionally in PSF, AVBT could result in over-correction and distal adding-on. We also found very low evidence to support that AIS patients treated with AVBT have superior muscle strength and endurance when compared to those treated with PSF.

CONCLUSIONS

AVBT provides better preservation of ROM and muscle strength postoperatively when compared with PSF, while achieving comparable curve correction. Future studies should explore the spinal growth trajectory to determine the window of opportunity for AVBT in AIS.

摘要

目的

椎体前路栓系术(AVBT)作为一种非融合治疗方法被引入,用于治疗青少年特发性脊柱侧凸(AIS),同时保留活动度(ROM)。这是第一项比较AVBT和后路脊柱融合术(PSF)治疗AIS时ROM结果的系统评价。

方法

我们在PubMed、EMBASE、MEDLINE和Cochrane图书馆进行了全面检索。纳入标准为接受AVBT或PSF或两者治疗的AIS患者,以及明确界定的ROM结果;排除标准为AIS以外的脊柱侧凸、生物力学或尸体研究、非英文出版物、病例报告、会议摘要、未发表的文献、评论和综述。主要结局是ROM。次要结局包括Cobb角矫正、生活质量(QOL)、并发症以及肌肉力量和耐力。

结果

本评价纳入了12项研究。我们发现有中等证据支持AVBT在ROM结果方面优于PSF,同时在低证据水平下实现了可比的Cobb角矫正。AVBT和PSF之间QOL结果的比较尚无定论。除了PSF中常见的并发症外,AVBT可能导致过度矫正和远端附加现象。我们还发现非常低的证据支持与接受PSF治疗的患者相比,接受AVBT治疗的AIS患者具有更好的肌肉力量和耐力。

结论

与PSF相比,AVBT术后能更好地保留ROM和肌肉力量,同时实现可比的曲线矫正。未来的研究应探索脊柱生长轨迹,以确定AVBT治疗AIS的时机窗口。

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