Maurer R G
Psychiatr Clin North Am. 1986 Jun;9(2):367-80.
Childhood autism is a syndrome characterized by a triad of abnormalities in social interaction, verbal and nonverbal communication, and imaginative activity. It is clinically heterogeneous, however, and probably represents a family of syndromes, each of which is the result of a different but related type of brain dysfunction. So far, there is no direct evidence for involvement of particular brain systems, although analogies to other disorders in humans and experimental animals do allow some plausible hypotheses.
儿童自闭症是一种以社交互动、言语和非言语交流以及想象活动方面的三联征异常为特征的综合征。然而,它在临床上具有异质性,可能代表了一系列综合征,其中每一种都是由不同但相关类型的脑功能障碍导致的。到目前为止,虽然与人类和实验动物的其他疾病进行类比确实能提出一些合理的假设,但尚无特定脑系统受累的直接证据。