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胃癌合并主动脉瘤同期手术治疗 1 例报告

Simultaneous operations for gastric cancer and aortic aneurysm: a case report.

机构信息

Department of Faculty Surgery No 1, Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Bolshaya Pirogovskaya Street 6, Moscow, 119435, Russia.

Department of Faculty Surgery No 2, Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Dovator Street 15, Moscow, 119048, Russia.

出版信息

J Med Case Rep. 2023 May 31;17(1):243. doi: 10.1186/s13256-023-03843-y.

Abstract

BACKGROUND

Gastric cancer is the second highest cause of morbidity among malignant tumors of the gastrointestinal tract and fifth in overall cancer statistics. Diseases of the cardiovascular system are the leading causes of death in the world. Aneurysm of the abdominal aorta is the most common type of vascular aneurysm, while in 75% of the cases it is asymptomatic. The risk of rupture of aneurysm of the abdominal aorta increases progressively depending on its diameter and the age of the patient.

CASE PRESENTATION

A 56-year-old male patient underwent treatment for complaints of pain and discomfort in the epigastric region, general weakness and difficulty in passing food through the esophagus. The neoplasm extended to the esophagus up to 17-20 mm (pT3N3aM0 R0 stage IIIB TNM 8). The aortic diameter at the level of the renal arteries was 18 mm; lower than the main renal arteries, an expansion of up to 60 mm was visualized; the length of aneurysm was 105 mm extending to the bifurcation. A gastrectomy with a resection of the lower thoracic esophagus and application of a manual double-row Roux-en -Y esophagojejunal anastomosis with cholecystectomy and D2 lymphadenectomy was done along with longitudinal aneurysmectomy and thrombectomy. The proximal anastomosis between the aorta and the synthetic linear prosthesis of 18 × 9 × 9 mm in the end-to-end type was formed by a continuous winding suture with the "Prolene" 5-0 thread. The end-to-end distal anastomosis of the prosthesis and aorta branch was formed by continuous winding suture with the "Prolene" 6-0 thread. The postoperative period proceeded without features and complications. On the 7th day after the surgery, the patient was discharged home in satisfactory condition.

CONCLUSIONS

Performing a simultaneous operation allowed the patient to undergo rehabilitation after the treatment of two diseases during one hospitalization and, in the shortest possible time, to proceed to the next stage of gastric cancer treatment-chemotherapy, thereby improving the prognosis of life expectancy. Also, one-stage surgical treatment of concomitant aneurysm of the abdominal aorta and gastric cancer is well tolerated and can avoid financial costs, and patient anxiety involved in a second operation.

摘要

背景

胃癌是胃肠道恶性肿瘤中发病率第二高的疾病,也是总体癌症统计中的第五大疾病。心血管系统疾病是世界上导致死亡的主要原因。腹主动脉瘤是最常见的血管动脉瘤类型,而在 75%的情况下,它是无症状的。腹主动脉瘤的破裂风险会随着其直径和患者年龄的增加而逐渐增加。

病例介绍

一名 56 岁男性患者因上腹部疼痛和不适、全身乏力以及食物通过食管困难而接受治疗。肿瘤延伸至食管达 17-20mm(pT3N3aM0 R0 期 IIIB TNM 8)。肾动脉水平的主动脉直径为 18mm;低于主肾动脉,可见到长达 60mm 的扩张;动脉瘤的长度为 105mm,延伸至分叉处。进行了胃切除术,切除了下段胸食管,并应用了手动双排 Roux-en-Y 食管空肠吻合术,同时进行了胆囊切除术和 D2 淋巴结清扫术,以及纵向动脉瘤切除术和血栓切除术。在端对端类型中,通过使用“Prolene”5-0 缝线进行连续缠绕缝合,将主动脉和 18×9×9mm 的合成线性假体之间形成近端吻合。使用“Prolene”6-0 缝线进行连续缠绕缝合,将假体和主动脉分支的远端吻合形成端对端吻合。术后过程无特征和并发症。手术后第 7 天,患者在满意的情况下出院回家。

结论

同时进行手术,使患者能够在一次住院期间同时治疗两种疾病,在最短的时间内进行下一阶段的胃癌治疗-化疗,从而改善预期寿命的预后。此外,腹主动脉瘤和胃癌的一期手术治疗耐受性良好,可避免二次手术带来的经济成本和患者焦虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1d1/10234076/423d1bcb0b68/13256_2023_3843_Fig1_HTML.jpg

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