Department of Traditional Chinese Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
The Second Clinical Medical College, Heilongjiang University of Chinese Medicine, Harbin, China.
Front Endocrinol (Lausanne). 2023 May 16;14:956772. doi: 10.3389/fendo.2023.956772. eCollection 2023.
Polycystic ovary syndrome (PCOS) is a reproductive endocrine disease characterized by menstrual disorders, infertility, and obesity, often accompanied by insulin resistance and metabolic disorders. The pathogenesis of PCOS is relatively complex and has a certain relationship with endocrine disorders. The increase of androgen and luteinizing hormone (LH) is the main cause of a series of symptoms. Traditional Chinese medicine (TCM) has obvious advantages and significant curative effects in the treatment of this disease. It can effectively reduce the insulin level of PCOS patients, regulate lipid metabolism, and increase ovulation rate and pregnancy rate and has fewer side effects. This article reviews the efficacy and safety of Chinese herbs and other TCM (such as acupuncture) in the treatment of PCOS and its complications in recent years, as well as the effect and mechanism on cellular endocrine, in order to provide a new clinical idea for the treatment of PCOS.
多囊卵巢综合征（PCOS）是一种生殖内分泌疾病，其特征是月经紊乱、不孕和肥胖，常伴有胰岛素抵抗和代谢紊乱。PCOS 的发病机制较为复杂，与内分泌失调有一定关系。雄激素和促黄体生成素（LH）的增加是一系列症状的主要原因。中医药在治疗该病方面具有明显的优势和显著的疗效，能有效降低 PCOS 患者的胰岛素水平，调节脂代谢，提高排卵率和妊娠率，且副作用较少。本文综述了近年来中药（如针灸）及其它中医治疗 PCOS 及其并发症的疗效和安全性，以及对细胞内分泌的影响和作用机制，以期为 PCOS 的治疗提供新的临床思路。
