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使用灌注指数对全身麻醉下的肿瘤骨科患者进行锁骨上阻滞评估:一项前瞻性队列研究。

Supraclavicular block evaluation in oncoorthopedic patients under general anesthesia using perfusion index: A prospective cohort study.

作者信息

Shah Shagun Bhatia, Jaipuria Jiten, Dubey Mamta, Vishnoi Gunjan, Chawla Rajiv, Bhargava Ajay Kumar

机构信息

Department of Anaesthesia and Critical Care, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, Delhi, India.

Department of Surgical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, Delhi, India.

出版信息

Saudi J Anaesth. 2023 Apr-Jun;17(2):155-162. doi: 10.4103/sja.sja_620_22. Epub 2023 Mar 10.

Abstract

BACKGROUND

Supraclavicular brachial plexus blocks (SCBPB) are routinely placed prior to anaesthetic induction for post-operative pain relief after prolonged orthopaedic oncosurgery, since patients are required to remain awake for sensorimotor evaluation of block. If the window period after surgery but before anesthesia-reversal is employed for administering SCBPB, it bestows the quadruple advantage of being painless, not augmenting surgical bleed, longer post-operative analgesia and reduced opioid-related side effects. The problem spot is assessing SCBPB-efficacy under general anesthesia.

METHODS

This prospective, single-centric, observational cohort study included 30 patients undergoing upper limb orthopaedic oncosurgery under general anesthesia. Perfusion index (PI) was assessed using two separate units of Radical-7™ finger pulse co-oximetry devices simultaneously in both the upper limbs and PI ratios calculated. Skin temperature was noted.

RESULTS

After successful block, PI values in blocked limb suddenly increased after 5 min, progressively increasing for next 10 min, whereas PI failed to increase further above that attained post anaesthetic-induction in unblocked limb. PI values in the blocked limb were 4.32, 4.49, 4.95, 7.25, 7.71, 7.90, 7.94, 7.89, and 7.93 at 0, 2, 3, 5, 10, and 15 min post block-institution at reversal and 2 min, 5 min post-reversal, respectively. PI ratios at 2, 3, 5, 10, and 15 min post block-administration in the blocked limb, taking PI at local anaesthetic injection as denominator were 1.04, 1.15, 1.67, 1.78, and 1.83, respectively. Correlation between PI and skin temperature in the blocked limb gave a repeated measures correlation coefficient of 0.79.

CONCLUSION

Monitoring trends in PI and PI-ratio in the blocked limb is a quantitative, non-invasive, inexpensive, simple, effective technique to monitor SCBPB-onset in anaesthetised patients.

摘要

背景

锁骨上臂丛神经阻滞(SCBPB)通常在长时间骨科肿瘤手术后的麻醉诱导前进行,用于术后疼痛缓解,因为患者需要保持清醒以进行神经阻滞的感觉运动评估。如果在手术后但在麻醉苏醒前的窗口期进行SCBPB,它具有无痛、不增加手术出血、延长术后镇痛时间和减少阿片类药物相关副作用这四重优势。问题在于评估全身麻醉下的SCBPB效果。

方法

这项前瞻性、单中心、观察性队列研究纳入了30例在全身麻醉下接受上肢骨科肿瘤手术的患者。使用两个独立的Radical-7™手指脉搏血氧饱和度仪同时评估双上肢的灌注指数(PI),并计算PI比值。记录皮肤温度。

结果

成功阻滞后,阻滞侧肢体的PI值在5分钟后突然升高,在接下来的10分钟内逐渐升高,而未阻滞侧肢体的PI值在达到麻醉诱导后的水平后未能进一步升高。阻滞侧肢体在阻滞开始后0、2、3、5、10和15分钟、苏醒时以及苏醒后2分钟、5分钟时的PI值分别为4.32、4.49、4.95、7.25、7.71、7.90、7.94、7.89和7.93。以局部麻醉注射时的PI为分母,阻滞侧肢体在给药后2、3、5、10和15分钟时的PI比值分别为1.04、1.15、1.67、1.78和1.83。阻滞侧肢体的PI与皮肤温度之间的相关性得出重复测量相关系数为0.79。

结论

监测阻滞侧肢体的PI和PI比值趋势是一种定量、无创、廉价、简单、有效的技术,可用于监测麻醉患者的SCBPB起效情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ae/10228879/6666620972de/SJA-17-155-g001.jpg

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