Department of Pharmacy, Hamad Bin Khalifa Medical City, Hamad Medical Corporation, Doha, Qatar.
Department of Pharmacy, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.
PLoS One. 2023 Jun 1;18(6):e0286419. doi: 10.1371/journal.pone.0286419. eCollection 2023.
With an increasingly strained health system budgets, healthcare services need to continually demonstrate evidence of economic benefits. This study sought to evaluate the economic impact of interventions initiated by clinical pharmacists in an adult general tertiary hospital.
A retrospective review of clinical pharmacist interventions was carried out throughout follow-up durations in March 2018, July/August 2018, and January 2019 in Hamad General Hospital (HGH) at Hamad Medical Corporation (HMC) in Qatar. The study included clinical pharmacy interventions data of patients admitted to the internal medicine, critical care, and emergency wards. Included interventions were documented by clinical pharmacists or clinical pharmacy specialists, and approved by physicians. Interventions by non-clinical pharmacists or with missing data were excluded. Adopting the perspective of HMC, we calculated the total economic benefit, which is the sum of the cost savings and the cost avoidance associated with the interventions. Cost savings was defined as the reduced cost of therapy associated with therapy changes minus the cost of intervention and cost avoidance was the cost avoided by eliminating the occurrence of adverse drug events (ADEs). Sensitivity analyses were performed to assess the robustness of results against uncertainties.
A total of 852 interventions, based on 340 patients, were included. The analysis projected an annual total benefit of QAR 2,267,036 (USD 621,106) based on a negative cost-savings of QAR-175,139 (USD-47,983) and a positive cost avoidance of QAR741,898 (USD203,260) over the 3-month follow-up period. The uncertainty analysis demonstrated the robustness of outcomes, including a 100% probability of positive economic benefit.
The clinical pharmacist intervention was associated with an increased cost of resource use, which was overtaken by the cost avoidance generated. The pharmacy intervention, therefore, is an overall economically beneficial practice in HGH, reducing ADEs with considerable consequential positive economic savings.
随着医疗系统预算的日益紧张,医疗保健服务需要不断证明其经济效益。本研究旨在评估临床药师在卡塔尔哈马德医疗保健公司(HMC)哈马德综合医院(HGH)成人综合三级医院中实施干预措施的经济影响。
对 2018 年 3 月、2018 年 7 月/8 月和 2019 年 1 月期间 HGH 内科、重症监护和急诊病房住院患者的临床药师干预进行了回顾性研究。包括由临床药师或临床药学专家记录并经医生批准的干预措施。排除非临床药师或数据缺失的干预措施。采用 HMC 的观点,我们计算了总经济效益,即与干预措施相关的成本节约和成本避免的总和。成本节约被定义为治疗改变相关的治疗成本降低减去干预成本,而成本避免是通过消除药物不良事件(ADE)的发生而避免的成本。进行敏感性分析以评估结果对不确定性的稳健性。
共纳入 340 例患者的 852 项干预措施。分析预计,在 3 个月的随访期间,基于成本节约负 QAR-175,139(USD-47,983)和成本避免正 QAR741,898(USD203,260),每年总效益为 QAR 2,267,036(USD 621,106)。不确定性分析表明结果具有稳健性,包括经济收益为正的概率为 100%。
临床药师干预与资源使用成本的增加有关,但被产生的成本避免所超越。因此,在 HGH 中,药学干预是一种整体上具有经济效益的实践,可减少 ADE 并带来可观的积极经济节约。