Al-Badriyeh Daoud, Aboelbaha Shimaa, ElShafey Nurhan, Al Hail Moza, El-Kassem Wessam, Abdulrouf Palli Valapila, Thomas Binny, Eljilany Islam, Alsalemi Noor, Syed Mariyam, Abushanab Dina
College of Pharmacy, QU Health, Qatar University, Doha, Qatar.
Department of Pharmacy, Drug Information Center, Hamad Bin Khalifa Medical City, Hamad Medical Corporation, Doha, Qatar.
Int J Clin Pharm. 2025 Jun 7. doi: 10.1007/s11096-025-01933-z.
Adverse drug events (ADEs) resulting from nonoptimized medication therapy significantly drive-up healthcare costs. Clinical pharmacists are pivotal in managing medication regimens, effectively reducing these associated expenses.
Given the scarcity of similar studies in the region, this study aimed to evaluate the overall economic impact of clinical pharmacists' interventions against ADEs at the Women's Wellness and Research Center (WWRC) in Qatar.
Analysis of the total economic benefit of clinical pharmacists' interventions was performed through a retrospective chart review of patients' records admitted during the periods of March 2018, July-August 2018, and January 2019. The current analysis was based on WWRC's perspective, in which the cost savings and cost avoidance associated with the interventions were used to determine the total economic benefit. A sensitivity analysis was conducted to determine the robustness of the results. The study was approved at the main public healthcare provider.
A total of 331 interventions for 162 patients were included in the analysis. The total economic benefit was estimated to be QAR169,320 (USD46,503), comprising cost avoidance of QAR170,995 (USD46,964) and negative resource-use cost savings of QAR-1675 (USD-460). The increase in resource use was primarily due to the addition of other medications to therapy. The sensitivity analysis confirmed that the outcomes are robust, demonstrating a 100% probability for positive economic benefits in all simulated cases.
Although there was an observed increase in resource utilization resulting from clinical pharmacists' interventions, this study highlights their crucial role in mitigating the costs associated with preventable adverse drug events.
药物治疗未优化导致的药物不良事件(ADEs)显著增加了医疗成本。临床药师在管理药物治疗方案方面起着关键作用,能有效降低这些相关费用。
鉴于该地区类似研究较少,本研究旨在评估卡塔尔妇女健康与研究中心(WWRC)临床药师针对ADEs进行干预的总体经济影响。
通过回顾性查阅2018年3月、2018年7 - 8月和2019年1月期间收治患者的病历,分析临床药师干预的总经济效益。当前分析基于WWRC的视角,其中与干预相关的成本节约和成本避免用于确定总经济效益。进行了敏感性分析以确定结果的稳健性。该研究在主要的公共医疗服务提供者处获得批准。
分析共纳入了162例患者的331次干预。总经济效益估计为169,320卡塔尔里亚尔(46,503美元),包括成本避免170,995卡塔尔里亚尔(46,964美元)和资源使用成本节约 - 1675卡塔尔里亚尔( - 460美元)。资源使用增加主要是由于治疗中添加了其他药物。敏感性分析证实结果是稳健的,在所有模拟案例中显示出正经济效益的概率为100%。
尽管观察到临床药师的干预导致资源利用增加,但本研究强调了他们在减轻与可预防药物不良事件相关成本方面的关键作用。