Center to Improve Veteran Involvement in their Care (CIVIC), VA Portland Health Care System, Portland, Oregon, USA.
Division of Pulmonary and Critical Care Medicine, Oregon Health and Science University, Portland, Oregon, USA.
J Palliat Med. 2023 Nov;26(11):1474-1481. doi: 10.1089/jpm.2023.0040. Epub 2023 Jun 1.
Hospice and palliative care (PC) are important components of lung cancer care and independently provide benefits to patients and their families. To better understand the relationship between hospice and PC and factors that influence this relationship. A retrospective cohort study of patients diagnosed with advanced lung cancer (stage IIIB/IV) within the U.S. Veterans Health Administration (VA) from 2007 to 2013 with follow-up through 2017 ( = 22,907). Mixed logistic regression models with a random effect for site, adjustment for patient variables, and propensity score weighting were used to examine whether the association between PC and hospice use varied by U.S. region and PC team characteristics. Overall, 57% of patients with lung cancer received PC, 69% received hospice, and 16% received neither. Of those who received hospice, 60% were already enrolled in PC. Patients who received PC had higher odds of hospice enrollment than patients who did not receive PC (adjusted odds ratio = 3.25, 95% confidence interval: 2.43-4.36). There were regional differences among patients who received PC; the predicted probability of hospice enrollment was 85% and 73% in the Southeast and Northeast, respectively. PC team and facility characteristics influenced hospice use in addition to PC; teams with the shortest duration of existence, with formal team training, and at lower hospital complexity were more likely to use hospice (all < 0.05). Among patients with advanced lung cancer, PC was associated with hospice enrollment. However, this relationship varied by geographic region, and PC team and facility characteristics. Our findings suggest that regional PC resource availability may contribute to substitution effects between PC and hospice for end-of-life care.
缓和医疗和姑息治疗(PC)是肺癌护理的重要组成部分,可独立为患者及其家属带来益处。为了更好地了解缓和医疗与姑息治疗之间的关系以及影响这种关系的因素,本研究采用美国退伍军人事务部(VA)2007 年至 2013 年期间诊断为晚期肺癌(IIIb/IV 期)并随访至 2017 年( = 22907)的患者进行回顾性队列研究。采用带有站点随机效应的混合逻辑回归模型、对患者变量进行调整以及倾向评分加权,以检验 PC 与临终关怀使用之间的关联是否因美国地区和 PC 团队特征而有所不同。总体而言,57%的肺癌患者接受了 PC,69%接受了临终关怀,16%两者均未接受。在接受临终关怀的患者中,60%已经接受了 PC。接受 PC 的患者比未接受 PC 的患者更有可能接受临终关怀(调整后的优势比 = 3.25,95%置信区间:2.43-4.36)。接受 PC 的患者之间存在地区差异;在东南部和东北部,接受 PC 的患者接受临终关怀的预测概率分别为 85%和 73%。除了 PC 外,PC 团队和设施特征也影响临终关怀的使用;存在时间最短、有正式团队培训以及医院复杂性较低的团队更有可能使用临终关怀(均 < 0.05)。在晚期肺癌患者中,PC 与临终关怀的使用相关。然而,这种关系因地理区域以及 PC 团队和设施特征而异。我们的研究结果表明,地区 PC 资源的可用性可能会导致 PC 和临终关怀在生命末期护理之间产生替代效应。