Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Int J Biol Macromol. 2023 Jul 1;242(Pt 4):124929. doi: 10.1016/j.ijbiomac.2023.124929. Epub 2023 May 30.
Cancer immunotherapy has favorable efficacy in various types of tumors, and has become an important weapon in the treatment of tumors in recent years. Long noncoding RNAs and microRNAs have been identified to play important roles in regulating cancer immunotherapy. Circular RNAs (circRNAs) are involved in the pathological process of many diseases, especially cancer. Many functions of circRNAs have been extensively studied. However, the functions of circRNAs in the tumor microenvironment and cancer immunotherapy do not appear to be fully elucidated. Therefore, we review the roles of circRNAs in tumor microenvironment and cancer immunotherapy.
癌症免疫疗法在各种类型的肿瘤中具有良好的疗效，近年来已成为肿瘤治疗的重要手段。长链非编码 RNA 和 microRNAs 已被确定在调节癌症免疫疗法中发挥重要作用。环状 RNA（circRNAs）参与许多疾病的病理过程，特别是癌症。circRNAs 的许多功能已被广泛研究。然而，circRNAs 在肿瘤微环境和癌症免疫治疗中的作用似乎尚未完全阐明。因此，我们综述了 circRNAs 在肿瘤微环境和癌症免疫治疗中的作用。
