Clinica Veterinaria Malpensa AniCura, Via G. Marconi, 27-21017 Samarate (VA), Italy (Brunati, Pintore, Valenti); Department of Veterinary Medical Sciences, University of Bologna, Via Zamboni, 33-40126 Bologna (BO), Italy (Avallone); Norad Diagnostica, Via Macchi, Via Engalfredo - 21017 Samarate (VA), Italy (Tomba); Department of Veterinary Sciences, University of Pisa, Viale delle Piagge, 2-56124 Pisa (PI), Italy (Cantile).
Can Vet J. 2023 Jun;64(6):529-533.
A 13-year-old, intact male mixed-breed dog was referred to our clinic for lethargy and asthenia following an episode of gastroenteritis. As an incidental finding during abdominal ultrasound, a mass on the right spermatic cord was seen. Cytology of the mass revealed a monomorphic population of large, round cells with a lymphoid appearance. A bilateral orchiectomy was conducted, and histopathology revealed the presence of a B-cell lymphoma in the right spermatic cord. Based on clinical staging, which showed no involvement of other sites, no additional treatment was administered. Recheck evaluations were scheduled for every 3 mo thereafter. Five months after surgery, the dog developed left central vestibular syndrome with a paradoxical right-sided head tilt. An MRI of the brain showed multifocal lesions and, due to a rapidly worsening clinical condition, the dog was humanely euthanized. The histopathology of the brain lesions was consistent with B-cell lymphoma. Key clinical message: This is the first report of a primary spermatic cord lymphoma relapsing to the brain in a dog. Although rare, spermatic cord tumors should be included among the differential diagnoses for masses arising from the spermatic cord. If lymphoma is diagnosed, location to other sites, especially to the central nervous system, should be considered.
一只 13 岁、完整的雄性混血犬因肠胃炎发作后出现嗜睡和乏力，被转诊至我院。在腹部超声检查中偶然发现右侧精索有一肿块。肿块的细胞学检查显示出一群形态单一的大圆形细胞，具有淋巴细胞外观。进行了双侧睾丸切除术，组织病理学显示右侧精索有 B 细胞淋巴瘤。根据没有其他部位受累的临床分期，未给予其他治疗。此后每 3 个月安排复查评估。手术后 5 个月，狗出现左侧中枢性前庭综合征，伴有反常的右侧头部倾斜。脑部 MRI 显示多灶性病变，由于临床状况迅速恶化，对狗进行了安乐死。脑部病变的组织病理学与 B 细胞淋巴瘤一致。关键临床信息：这是首例犬原发性精索淋巴瘤复发至脑部的报告。虽然罕见，但精索肿瘤应包括在精索肿块的鉴别诊断中。如果诊断为淋巴瘤，则应考虑到其他部位，特别是中枢神经系统的位置。
