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保留瓣膜主动脉根部置换术改良David V再植入技术的长期经验。

Long-term experience of the modified David V re-implantation technique for valve-sparing aortic root replacement.

作者信息

Sarikaya Sabit, Kirali Kaan

机构信息

Department of Cardiovascular Surgery, Kosuyolu Heart Training and Research Hospital, Istanbul, Turkey. Email:

Department of Cardiovascular Surgery, Kosuyolu Heart Training and Research Hospital, Istanbul, Turkey.

出版信息

Cardiovasc J Afr. 2023 Jun 1;34:1-8. doi: 10.5830/CVJA-2023-018.

Abstract

OBJECTIVE

The modified David V technique is one of the valve-sparing aortic root replacement (V-SARR) techniques, which is an alternative to traditional composite valve graft root replacement techniques. We aimed to analyse our long-term experience with the modified David V re-implantation technique for the treatment of aortic root aneurysm and significant aortic valve insufficiency.

METHODS

From March 2009 to November 2021 the modified David V re-implantation technique, one of the V-SARR techniques, was performed on 48 patients in our centre. The results were analysed retrospectively. Two different-sized grafts were used in all patients. The grafts used in the proximal position were larger than the distal grafts. We performed both intra-operative and post-procedural transoesophageal echocardiography on each patient. All patients were followed by means of transthoracic echocardiography. The mean follow-up period was 5.7 ± 3.1 years.

RESULTS

The mean age of this cohort was 56.3 ± 14.3 years (24-79) and the majority were men (75%). The mean aortic root diameter was 5.1 ± 0.6 cm. The mean diameter for the assending aorta was 5.4 ± 2.1 cm. The in-hospital mortality rate was 4.2% ( = 2). One patient needed aortic valve replacement in the early postoperative period. Two (4.2%) patients died in the early postoperative period and four (8.3%) died in the late postoperative period. Overall survival was 91 ± 4 and 86 ± 5% at one and five years, respectively. Aortic valve insufficiency was at moderate levels postoperatively. Freedom from moderate to severe residual aortic insufficiency was 89.6% at 10 years. None of the patients needed late re-operation of the aortic valve postoperatively. Freedom from valve re-operation was 100% at the end of the follow up.

CONCLUSION

Our study shows that the David V technique is associated with excellent long-term durability, a remarkably low rate of valve-related complications, and it protects the re-implanted native aortic valve from a second operation. Additionally this technique could be safely implemented in patients with a bicuspid aortic valve and acute type A aortic dissection without leaflet deformity.

摘要

目的

改良David V技术是保留瓣膜的主动脉根部置换术(V-SARR)之一,是传统复合瓣膜移植根部置换技术的替代方法。我们旨在分析采用改良David V再植入技术治疗主动脉根部瘤和严重主动脉瓣关闭不全的长期经验。

方法

2009年3月至2021年11月,我们中心对48例患者实施了改良David V再植入技术,这是V-SARR技术之一。对结果进行回顾性分析。所有患者均使用了两种不同尺寸的移植物。近端使用的移植物比远端移植物大。我们对每位患者均进行了术中及术后经食管超声心动图检查。所有患者均通过经胸超声心动图进行随访。平均随访时间为5.7±3.1年。

结果

该队列的平均年龄为56.3±14.3岁(24 - 79岁),大多数为男性(75%)。平均主动脉根部直径为5.1±0.6 cm。升主动脉平均直径为5.4±2.1 cm。住院死亡率为4.2%(n = 2)。1例患者术后早期需要进行主动脉瓣置换。2例(4.2%)患者术后早期死亡,4例(8.3%)患者术后晚期死亡。1年和5年的总体生存率分别为91±4%和86±5%。术后主动脉瓣关闭不全为中度。10年时无中度至重度残余主动脉瓣关闭不全的比例为89.6%。术后无患者需要进行主动脉瓣晚期再次手术。随访结束时瓣膜再次手术的无事件生存率为100%。

结论

我们的研究表明,David V技术具有出色的长期耐久性、极低的瓣膜相关并发症发生率,并且能使再植入的自体主动脉瓣免于二次手术。此外,该技术可安全应用于患有二叶式主动脉瓣和无瓣叶畸形的急性A型主动脉夹层患者。

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