联合 5-氨基酮戊酸光动力疗法、手术和司库奇尤单抗治疗重度化脓性汗腺炎。
Treatment of severe hidradenitis suppurativa with a combination of 5-aminolevulinic acid photodynamic therapy, surgery, and secukinumab.
机构信息
Department of Dermatology, BenQ Medical Center, The Affiliated BenQ Hospital of Nanjing Medical University, Nanjing, Jiangsu 210019, China.
Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, Jiangsu 210042, China.
出版信息
Photodiagnosis Photodyn Ther. 2023 Jun;42:103637. doi: 10.1016/j.pdpdt.2023.103637. Epub 2023 Jun 1.
Hidradenitis suppurativa (HS) is a chronic inflammatory disease characterized by nodules, abscesses, fistulas, sinus tracts, and scars, typically in intertriginous areas (Sabat et al., 2022). Therapeutic options include medications, surgical interventions, and physiotherapy; however, clinical management is challenging. We report a case of HS that was refractory to multiple treatments and achieved complete remission with a combination therapy of surgery, 5-aminolevulinic acid photodynamic therapy (ALA-PDT), and secukinumab.
化脓性汗腺炎（HS）是一种慢性炎症性疾病，其特征为结节、脓肿、瘘管、窦道和瘢痕，通常发生于皱褶部位（Sabat 等人，2022 年）。治疗选择包括药物治疗、手术干预和物理治疗；然而，临床管理具有挑战性。我们报告了一例对多种治疗方法均无反应的 HS 病例，通过手术、5-氨基酮戊酸光动力疗法（ALA-PDT）和司库奇尤单抗联合治疗实现了完全缓解。
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