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联合 5-氨基酮戊酸光动力疗法、手术和司库奇尤单抗治疗重度化脓性汗腺炎。

Treatment of severe hidradenitis suppurativa with a combination of 5-aminolevulinic acid photodynamic therapy, surgery, and secukinumab.

机构信息

Department of Dermatology, BenQ Medical Center, The Affiliated BenQ Hospital of Nanjing Medical University, Nanjing, Jiangsu 210019, China.

Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, Jiangsu 210042, China.

出版信息

Photodiagnosis Photodyn Ther. 2023 Jun;42:103637. doi: 10.1016/j.pdpdt.2023.103637. Epub 2023 Jun 1.

DOI:10.1016/j.pdpdt.2023.103637
PMID:37268043
Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory disease characterized by nodules, abscesses, fistulas, sinus tracts, and scars, typically in intertriginous areas (Sabat et al., 2022). Therapeutic options include medications, surgical interventions, and physiotherapy; however, clinical management is challenging. We report a case of HS that was refractory to multiple treatments and achieved complete remission with a combination therapy of surgery, 5-aminolevulinic acid photodynamic therapy (ALA-PDT), and secukinumab.

摘要

化脓性汗腺炎(HS)是一种慢性炎症性疾病,其特征为结节、脓肿、瘘管、窦道和瘢痕,通常发生于皱褶部位(Sabat 等人,2022 年)。治疗选择包括药物治疗、手术干预和物理治疗;然而,临床管理具有挑战性。我们报告了一例对多种治疗方法均无反应的 HS 病例,通过手术、5-氨基酮戊酸光动力疗法(ALA-PDT)和司库奇尤单抗联合治疗实现了完全缓解。

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1
Treatment of severe hidradenitis suppurativa with a combination of 5-aminolevulinic acid photodynamic therapy, surgery, and secukinumab.联合 5-氨基酮戊酸光动力疗法、手术和司库奇尤单抗治疗重度化脓性汗腺炎。
Photodiagnosis Photodyn Ther. 2023 Jun;42:103637. doi: 10.1016/j.pdpdt.2023.103637. Epub 2023 Jun 1.
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5-ALA PDT successfully treats facial hidradenitis suppurativa-induced severe hypertrophic scar.5-ALA PDT 成功治疗面部化脓性汗腺炎所致严重增生性瘢痕。
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Aminolevulinic acid photodynamic therapy for hidradenitis suppurativa.氨基乙酰丙酸光动力疗法治疗化脓性汗腺炎
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Treatment of hidradenitis suppurativa with intralesional photodynamic therapy with 5-aminolevulinic acid and 630nm laser beam.采用5-氨基酮戊酸及630nm激光束进行皮损内光动力疗法治疗化脓性汗腺炎。
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Effectiveness of 5-aminolevulinic acid photodynamic therapy in the treatment of hidradenitis suppurativa: a report of 5 cases.5-氨基酮戊酸光动力疗法治疗化脓性汗腺炎的疗效:5例报告
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Treatment of recalcitrant hidradenitis suppurativa with photodynamic therapy: report of five cases.光动力疗法治疗顽固性化脓性汗腺炎:5例报告
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Photodynamic therapy combined with surgery for hidradenitis suppurativa: A case report.光动力疗法联合手术治疗化脓性汗腺炎:一例报告。
Photodiagnosis Photodyn Ther. 2019 Dec;28:8-9. doi: 10.1016/j.pdpdt.2019.07.024. Epub 2019 Jul 27.

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