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左房应变可预测行经皮二尖瓣交界分离术的重度风湿性二尖瓣狭窄患者左房功能的改善。

Left atrial strain predicts improvement in left atrial functions of severe rheumatic mitral stenoses undergoing successful percutaneous transmitral commissurotomy.

机构信息

Department of Cardiology, Command Hospital, Udhampur, Jammu and Kashmir, India.

Department of Cardiology, SGRRIMHS & Mahant Inderish Hospital, Dehradun, India.

出版信息

Echocardiography. 2023 Jul;40(7):642-646. doi: 10.1111/echo.15627. Epub 2023 Jun 4.

Abstract

AIMS

Chronic rheumatic heart disease (RHD) is prevalent in India. The mitral valve in isolation or combination with the aortic or tricuspid valve is involved in 31.6% and 52.8% of chronic RHD patients, respectively. The left atrium (LA) functions as a reservoir during the cardiac cycle. Therefore, the LA enlargement leads to longitudinal lengthening, measured as a positive strain, permitting the measurement of the longitudinal strain of LA. This study aimed to assess the LA functions using peak atrial longitudinal strain (PALS) in patients with severe rheumatic mitral stenoses (MS) in sinus rhythm who underwent successful percutaneous transvenous mitral commissurotomy (PTMC).

MATERIAL AND METHODS

We recruited 56 patients with severe rheumatic MS for the study, of which 06 PTMC procedures were considered unsuccessful. So, 50 patients of chronic severe rheumatic MS in sinus rhythm undergoing PTMC were enrolled in a tertiary care centre of the Armed Forces from August 2017 to May 2019. Patients included in the study were not consecutive, and patients with atrial fibrillation (AF) were excluded.

RESULTS

PALS improved post-PTMC (P < .001) in this study, effectively concluding that PALS is impaired in patients with severe symptomatic MS and is acutely enhanced after treatment.

CONCLUSIONS

PALS is a good indicator of LA function and may predict the success of PTMC on the rheumatic mitral valve.

摘要

目的

慢性风湿性心脏病(RHD)在印度较为普遍。孤立或联合主动脉瓣或三尖瓣的二尖瓣分别占慢性 RHD 患者的 31.6%和 52.8%。左心房(LA)在心脏周期中充当储液器。因此,LA 增大导致纵向伸长,表现为正应变,从而可以测量 LA 的纵向应变。本研究旨在评估窦性心律下成功行经皮经静脉二尖瓣交界切开术(PTMC)的严重风湿性二尖瓣狭窄(MS)患者的 LA 功能,使用峰值心房纵向应变(PALS)进行评估。

材料和方法

我们招募了 56 名窦性心律下患有严重风湿性 MS 的患者进行研究,其中 06 例 PTMC 手术被认为不成功。因此,我们在 2017 年 8 月至 2019 年 5 月期间从一家三级保健中心招募了 50 名窦性心律下接受 PTMC 的慢性严重风湿性 MS 患者。纳入研究的患者并非连续,且排除了心房颤动(AF)患者。

结果

本研究中,PTMC 后 PALS 改善(P<.001),这有效表明 PALS 在严重有症状性 MS 患者中受损,且在治疗后急性增强。

结论

PALS 是 LA 功能的良好指标,可能预测风湿性二尖瓣的 PTMC 成功率。

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