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韩国类风湿关节炎患者的关节置换手术:大型国家数据库分析。

Joint Replacement Surgery in Patients with Rheumatoid Arthritis in South Korea: Analysis of a Large National Database.

机构信息

Department of Orthopedic Surgery, National Health Insurance Service Ilsan Hospital, Goyang, Korea.

Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Clin Orthop Surg. 2023 Jun;15(3):395-401. doi: 10.4055/cios21274. Epub 2022 Nov 24.

DOI:10.4055/cios21274
PMID:37274496
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10232310/
Abstract

BACKGROUND

We aimed to investigate the current trend of joint replacement surgery incidence in patients with rheumatoid arthritis (RA) in South Korea and to compare the incidence of joint replacement surgery in each affected joint.

METHODS

We performed this big data analysis to investigate the current trend of joint replacement surgery incidence in patients with RA in South Korea and to compare the incidence of joint replacement surgery in each affected joint. This retrospective study was based on data from the Korea National Health Insurance claims database.

RESULTS

The prevalence of RA increased every year (0.13% in 2008, 0.25% in 2016). The number of newly diagnosed patients increased from 29,184 in 2010 to 38,347 in 2016. The incidence rate of joint replacement surgery in patients with RA increased from 0.72% in 2010 to 4.03% in 2016. The knee (68.3%) was the most commonly replaced joint. The relative risk (RR) of additional joint replacement surgery was highest for the shoulder joint (RR,1.454; 95% confidence interval, 0.763-2.771). The median time from diagnosis to surgery was the shortest in the elbow joint (379 days) and the longest in the shoulder joint (955 days). The median time for each joint was short in order of the elbows, ankles, hips, knees, and shoulders ( < 0.01).

CONCLUSIONS

The most frequently and initially replaced joints were different, but the prevalence and incidence of RA, as well as those of joint replacement surgery, have recently increased in South Korea. Joint replacement surgery in RA was the highest for the knee joint. The median time from diagnosis to surgery was shortest for the elbow, followed by the ankle, hip, knee, and shoulder. Regardless of whether patients are symptomatic, evaluation of large joints such as the knee, elbow, ankle, and hip should be considered from an early stage.

摘要

背景

本研究旨在调查韩国类风湿关节炎(RA)患者关节置换手术的发生率趋势,并比较各受累关节的关节置换手术发生率。

方法

本回顾性研究基于韩国国家健康保险索赔数据库的数据,旨在调查韩国 RA 患者关节置换手术的发生率趋势,并比较各受累关节的关节置换手术发生率。

结果

RA 的患病率逐年增加(2008 年为 0.13%,2016 年为 0.25%)。新诊断患者人数从 2010 年的 29184 例增加到 2016 年的 38347 例。RA 患者的关节置换手术发生率从 2010 年的 0.72%增加到 2016 年的 4.03%。膝关节(68.3%)是最常置换的关节。肩关节(RR,1.454;95%置信区间,0.763-2.771)的额外关节置换手术的相对风险最高。从诊断到手术的中位时间在肘关节最短(379 天),在肩关节最长(955 天)。每个关节的中位时间顺序为肘关节、踝关节、髋关节、膝关节和肩关节(<0.01)。

结论

最常置换和最初置换的关节不同,但韩国 RA 的患病率和发病率以及关节置换手术的发病率最近均有所增加。RA 的关节置换手术中膝关节发生率最高。从诊断到手术的中位时间最短的是肘关节,其次是踝关节、髋关节、膝关节和肩关节。无论患者是否有症状,都应考虑从早期开始评估膝关节、肘关节、踝关节和髋关节等大关节。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f1e/10232310/d498db589667/cios-15-395-g008.jpg
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