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[不同乙醇睡眠时长动物大脑中多巴胺和γ-氨基丁酸系统功能的特征]

[Characteristics of dopamine and GABA system functions in the brain of animals with different durations of ethanol sleep].

作者信息

Kanunnikova N P, Koval'chuk V G

出版信息

Vopr Med Khim. 1986 May-Jun;32(3):52-5.

PMID:3727469
Abstract

Uptake of labelled dopamine and GABA and activities of GABA transaminase, dehydrogenase and reductase of succinic semialdehyde were studied in brain of rats with different duration of ethanol narcosis. The data obtained showed the differences in activities of the dopamine and GABA systems, which were not similar in different brain regions. These differences were manifested by both initial activities (hemispheres, brain stem) and different changes of these systems after the ethanol injection (basal ganglia, hemispheres).

摘要

研究了不同乙醇麻醉时长的大鼠脑内标记多巴胺和γ-氨基丁酸(GABA)的摄取情况,以及GABA转氨酶、脱氢酶和琥珀酸半醛还原酶的活性。所得数据显示多巴胺和GABA系统的活性存在差异,且在不同脑区并不相同。这些差异在初始活性(大脑半球、脑干)以及乙醇注射后这些系统的不同变化(基底神经节、大脑半球)中均有体现。

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