Tan A T, Dular R, Innes I R
Prog Biochem Pharmacol. 1981;18:224-30.
The uptake of (3H)dopamine into nerve endings (synaptosomes) isolated from cortex and brain stem of rats under various stages of ethanol intoxication were studied. Acute or chronic ethanol treatment inhibited the high affinity uptake of dopamine into both regions by about 30% when rats were still under ethanol. The inhibition in brain stem persisted even after 120 h of withdrawal from ethanol. In cortex, 16 h after acute treatment, the uptake was slightly (about 10%) elevated from that of control in contrast to chronic rats, which were 43 and 41% more than that of the control after withdrawal from ethanol for 48 and 120 h, respectively.
研究了在乙醇中毒不同阶段从大鼠皮层和脑干分离出的神经末梢（突触体）对（3H）多巴胺的摄取情况。当大鼠仍处于乙醇作用下时，急性或慢性乙醇处理会使多巴胺在这两个区域的高亲和力摄取受到约30%的抑制。即使在戒断乙醇120小时后，脑干中的这种抑制作用仍然存在。在皮层中，急性处理16小时后，摄取量相比对照组略有升高（约10%），而慢性处理的大鼠在戒断乙醇48小时和120小时后，摄取量分别比对照组高43%和41%。
