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适应不良患者的临床管理。

The Clinical Management of Deconditioned Patient.

机构信息

Belgorod State University, 85, Pobedy St., Belgorod, 308015, Russia.

Federal State Budgetary Educational Institution of Higher Education «Kursk State Medical University» of the Ministry of Health of the Russian Federation, 3, Karl Marx Street, Kursk, 305004, Russia.

出版信息

Arch Razi Inst. 2022 Dec 31;77(6):2251-2258. doi: 10.22092/ARI.2022.360062.2542. eCollection 2022 Dec.

Abstract

The current study was designed to investigate the clinical management of deconditioned patients. In the current study, we investigate the clinical manifestations of deconditioned patients. A subacute functional deficiency was determined when getting up from a supine position and developing tachycardia with an increase in heart rate by 30 or more per minute for 10 minutes. This study included 172 elderly patients aged 65 to 74 years. The average age of the patients was 69.2+2.2 years. There were 102 men and 70 women in the study. These patients were registered at the dispensary with the therapists of outpatient clinics after an infectious disease. Within 6 months after the treatment, a comprehensive geriatric assessment of patients was performed. All patients were divided into four groups depending on the indicators of motor activity, which in the framework of this study was the criterion of the adaptive function of the body and viability. Patients with normal motor activity indicators did not have the decondition and were designated as a control group. Patients with the decondition did not have normal indicators of motor activity. The obtained results were processed statistically. According to the results of our study, it was noted that the assessment of the six months after the treatment showed heterogeneity of patients from a functional point of view with a homogeneous somatic structure. Six months after the treatment, out of 172 people, 45 people (26.2%) had normal motor activity indicators (39-40 points); according to the questionnaire "Assessment of motor activity in the elderly", the average score was 39.6+0.2; 42 people (24.4%) had mild motor activity disorders (34-38 points), the average score was 36.1+0.4; moderate disorders (21-33 points) were registered in 47 people (27.3%), the average score was 27.9+2.1; significant motor activity disorders (0-20 points) occurred in 38 people (22.1%), the average score was 13.2+1.4. The fall syndrome was characteristic of those patients with the decondition who demonstrated moderate and significant motor activity disorders 6 months after the treatment. In particular, in people with significant motor activity disorders, there was a decrease in muscle strength in the lower extremities by 48.3+3.2% and in the upper extremities - by 27.1+3.1% (<0.05). As a result of the presence of the decondition, an unfavorable cascade of geriatric syndromes is formed in the form of an increase in the level of situational anxiety from 21.9-24.8 to 58.4-75.3 points on the Spielberger-Hanin scale, a deterioration in morale with an increase in the severity of depression from 5.8-6.0 to 11.0-14.9 points, a decrease in the quality of sleep on the ten-point visual analog scale from 8.3-8.4 to 5.2-5.7 points on the Beck scale, an increase in the proportion of patients at risk of developing malnutrition syndrome from 4.8-6.7% to 46.8-68.4%, the development of the fall syndrome, which, in turn,, it is a predictor of the development of dinapenia in the form of a decrease in the strength of the upper extremities by 22.7-27.1%, a decrease in the strength of the lower extremities by 29.6-49.6%, with a faster rate of decrease in the strength of the lower extremities compared to the upper extremities by 1.8 times, which, accordingly, reduces the rehabilitation potential. Clinical manifestations of the decondition in elderly patients were such geriatric syndromes as anxiety, depression, cognitive decline, sleep disorders, hypomobility, dinapenia, risk of developing malnutrition syndrome and falls syndrome.

摘要

本研究旨在探讨去适应患者的临床管理。在当前研究中,我们调查了去适应患者的临床表现。当从仰卧位起身并出现心动过速,心率每分钟增加 30 次或更多持续 10 分钟时,即可确定亚急性功能减退。本研究纳入了 172 名年龄在 65 至 74 岁的老年患者。患者的平均年龄为 69.2+2.2 岁。研究中有 102 名男性和 70 名女性。这些患者在感染性疾病后在门诊诊所由治疗师登记在诊所以外。在治疗后 6 个月内,对患者进行了全面的老年评估。所有患者均根据运动活动指标分为四组,在本研究框架内,该指标是身体适应性功能和生存能力的标准。运动活动指标正常的患者没有去适应,被指定为对照组。运动活动指标异常的患者没有去适应。对获得的结果进行了统计学处理。根据我们的研究结果,治疗后 6 个月的评估显示,从功能角度来看,患者具有异质性,而躯体结构则具有同质性。治疗后 6 个月,172 人中 45 人(26.2%)运动活动指标正常(39-40 分);根据“老年人运动活动评估”问卷,平均得分为 39.6+0.2;42 人(24.4%)运动活动轻度障碍(34-38 分),平均得分为 36.1+0.4;47 人(27.3%)中度障碍(21-33 分),平均得分为 27.9+2.1;38 人(22.1%)严重运动活动障碍(0-20 分),平均得分为 13.2+1.4。在治疗后 6 个月,去适应的患者表现出中度和严重的运动活动障碍,其特征为跌倒综合征。特别是在严重运动活动障碍的患者中,下肢肌肉力量下降 48.3+3.2%,上肢肌肉力量下降 27.1+3.1%(<0.05)。由于存在去适应,形成了一种不利的老年综合征级联,表现为情境焦虑程度从斯皮尔伯格-哈宁量表的 21.9-24.8 分增加到 58.4-75.3 分,士气恶化,抑郁严重程度从 5.8-6.0 分增加到 11.0-14.9 分,贝克量表上的睡眠质量从 8.3-8.4 分下降到 5.2-5.7 分,有发展营养综合征风险的患者比例从 4.8-6.7%增加到 46.8-68.4%,跌倒综合征的发展,这反过来又是肌肉减少症的发展的预测因子,表现为上肢力量下降 22.7-27.1%,下肢力量下降 29.6-49.6%,下肢力量下降速度比上肢快 1.8 倍,这相应地降低了康复潜力。老年患者去适应的临床表现为焦虑、抑郁、认知能力下降、睡眠障碍、活动减少、肌肉减少症、营养不良综合征风险和跌倒综合征。

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