Deva Faizah Ashfah Latief
Department of ENT and HNS, GMC and SMGS Hospital, Jammu, Jammu and Kashmir India.
Indian J Otolaryngol Head Neck Surg. 2023 Jun;75(2):753-759. doi: 10.1007/s12070-022-03457-8. Epub 2023 Jan 11.
To assess the diagnostic accuracy of NBI endoscopy for the diagnosis of early recurrent laryngeal and hypopharyngeal cancers after radiotherapy. The study was conducted over a period of two and a half years from June 2019 to February 2022 and included 123 post-RT patients with laryngeal and hypopharyngeal cancers. The patients were planned for endoscopy with white light and narrow-band imaging. The biopsy was carried out in NBI suspected lesions and sent for histopathological examination. The pathologist was blinded to the outcome of NBI and WLE results to eliminate observer bias. The age group most commonly affected in our study was 40-50 years. Out of the 123 patients, 106 were males and 17 were females. The overall Sensitivity, Specificity, Positive predictive value and Negative predictive value of NBI for malignant lesions were 90.6%, 99%, 95.2% and 98% respectively. NBI Technology is a first-rate diagnostic tool that can help in diagnosing early recurrent cancer lesions, especially after RT, in which the recurrence is otherwise difficult to differentiate from post-radiotherapy oedema. This technology can significantly reduce the rates of failure to detect cancers in early stages.
评估窄带成像（NBI）内镜检查对放疗后早期喉癌和下咽癌复发的诊断准确性。该研究于2019年6月至2022年2月的两年半时间内进行，纳入了123例放疗后的喉癌和下咽癌患者。对患者进行了白光和窄带成像内镜检查。在NBI怀疑有病变的部位进行活检，并送去做组织病理学检查。病理学家对NBI和白光内镜检查（WLE）结果不知情，以消除观察者偏倚。我们研究中最常受影响的年龄组为40 - 50岁。在123例患者中，男性106例，女性17例。NBI对恶性病变的总体敏感性、特异性、阳性预测值和阴性预测值分别为90.6%、99%、95.2%和98%。NBI技术是一种一流的诊断工具，有助于诊断早期复发癌病变，尤其是放疗后的复发癌，否则其复发难以与放疗后水肿相鉴别。该技术可显著降低早期癌症漏诊率。
