From the Departments of Nuclear Medicine.
Hematology.
Clin Nucl Med. 2023 Aug 1;48(8):694-696. doi: 10.1097/RLU.0000000000004728. Epub 2023 Jun 6.
Abdominal contrast-enhanced CT was performed in a 61-year-old man with difficulties of urination and defecation for 4 months, which revealed huge rectal masses involving multiple adjacent organs, suspected as malignant lesions. 18 F-FDG PET/CT was subsequently performed for staging. The images showed intense FDG uptake and slightly hyperdense masses involving rectum, bladder, prostate, left ureter, and the anterior abdominal wall at the level of the pelvic cavity. Histopathological examination confirmed the masses were due to malakoplakia, which displayed as abundant von Hansemann cells aggregated and infiltrated in lesions, with distinctive cytoplasmic inclusions termed Michaelis-Gutmann bodies.
一位 61 岁男性出现排尿和排便困难 4 个月，行腹部增强 CT 检查，结果显示直肠内巨大肿块累及多个相邻器官，考虑为恶性病变。随后行 18 F-FDG PET/CT 分期检查。图像显示直肠、膀胱、前列腺、左侧输尿管和盆腔水平的前腹壁有强烈的 FDG 摄取和稍高密度肿块。组织病理学检查证实肿块为类脂质蛋白沉积症，表现为大量 von Hansemann 细胞聚集和浸润在病变中，细胞质内有特征性的包涵体，称为 Michaelis-Gutmann 小体。
