玫瑰花结引导中胚层 MET 的方向。

Rosettes guide the way for mesodermal MET.

机构信息

Section of Developmental Biology, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

出版信息

Dev Cell. 2023 Jun 5;58(11):917-918. doi: 10.1016/j.devcel.2023.04.018.

DOI:10.1016/j.devcel.2023.04.018

PMID:37279697

Abstract

Mesenchymal-epithelial transition (MET) is a critical process in development, guiding tissue morphogenesis. In this issue of Developmental Cell, two studies, one by Gredler et al. and one by Abboud Asleh et al., reveal how multicellular rosettes critically contribute to MET in earliest notochord and lateral plate mesoderm formation, respectively.

摘要

间质上皮转化 (MET) 是发育过程中的一个关键过程，指导组织形态发生。在本期《发育细胞》中，Gredler 等人和 Abboud Asleh 等人的两项研究分别揭示了多细胞玫瑰花结如何分别对早期脊索和侧板中胚层形成中的 MET 起关键作用。