Hsieh K S, Sanders S P, Colan S D, MacPherson D, Holland C
Am Heart J. 1986 Jul;112(1):103-7. doi: 10.1016/0002-8703(86)90686-1.
Although the clinical utility of right ventricular (RV) systolic time intervals (STI) has been well documented, their use is at times limited by an inability to obtain adequate M-mode echocardiographic images of the pulmonary valve. Therefore the relationship between the pulmonary artery Doppler flow tracing and the timing of pulmonary valve opening and closure was investigated to determine if the more readily available Doppler recording could be utilized for determining RV STIs. We compared RV preejection period (PEP), ejection time (VET), and PEP/VET ratio derived from the pulsed Doppler frequency-time curve recorded in the main pulmonary artery with measurements from a simultaneously recorded M-mode pulmonary valve echocardiogram (Echo). The nadir of the late systolic flow reversal, rather than the point at which the frequency spectrum crosses the zero baseline, correlated best with the point of pulmonary valve closure. By the use of this method for determining end-systole, all three Doppler-derived measurements were highly correlated with the values from the pulmonary valve echocardiogram: PEPEcho = 1.01 PEPDoppler - 3.1 (r = 0.990, S.E.E. PEPEcho = 2.7 msec); VETEcho = 0.98 VETDoppler + 10.2 (r = 0.998, S.E.E. VETEcho = 3.3 msec); (PEP/VET)Echo = 0.95 (PEP/VET)Doppler + 0.007 (r = 0.980, S.E.E. (PEP/VET)Echo = 0.012 msec). The Doppler velocity-time curve provides accurate measurement of RV STIs that can be recorded with relative ease compared with the pulmonary valve echocardiogram. This expanded availability of RV STIs permits an improved ability to investigate the hemodynamic determinants of these indices and their relation to the status of the pulmonary vasculature and right ventricular performance.
尽管右心室（RV）收缩时间间期（STI）的临床效用已有充分记录，但它们的应用有时会受到无法获得肺动脉瓣足够的M型超声心动图图像的限制。因此，研究了肺动脉多普勒血流描记与肺动脉瓣开放和关闭时间的关系，以确定更容易获得的多普勒记录是否可用于确定右心室STI。我们将从主肺动脉记录的脉冲多普勒频率-时间曲线得出的右心室射血前期（PEP）、射血时间（VET）和PEP/VET比值与同时记录的M型肺动脉瓣超声心动图（Echo）测量值进行了比较。收缩晚期血流逆转的最低点，而不是频谱与零基线交叉的点，与肺动脉瓣关闭点的相关性最好。通过使用这种确定收缩末期的方法，所有三个多普勒衍生测量值与肺动脉瓣超声心动图的值高度相关：PEPEcho = 1.01 PEPDoppler - 3.1（r = 0.990，标准误差PEPEcho = 2.7毫秒）；VETEcho = 0.98 VETDoppler + 10.2（r = 0.998，标准误差VETEcho = 3.3毫秒）；（PEP/VET）Echo = 0.95（PEP/VET）Doppler + 0.007（r = 0.980，标准误差（PEP/VET）Echo = 0.012毫秒）。与肺动脉瓣超声心动图相比，多普勒速度-时间曲线能够相对轻松地记录右心室STI的准确测量值。右心室STI的这种更广泛的可用性提高了研究这些指标的血流动力学决定因素及其与肺血管系统状态和右心室功能关系的能力。
