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咽成形术有效吗?10年间连续100例手术的结果。

Does pharyngoplasty work? Outcomes of 100 consecutive operations over 10 years.

作者信息

Haydon Nicholas, Semple Harriet, Ho Kevin, Boorer Catherine

机构信息

Department of Plastic & Reconstructive Surgery, Sydney Children's Hospital, Sydney, New South Wales, Australia.

出版信息

ANZ J Surg. 2023 Jul-Aug;93(7-8):1944-1949. doi: 10.1111/ans.18563. Epub 2023 Jun 7.

Abstract

BACKGROUND

Velopharyngeal insufficiency is a commonly encountered problem in Cleft Surgery, with pharyngoplasty being the mainstay of surgical management. In this study we aim to investigate the indications and outcomes of a single institution's experience and compare to international literature.

METHODS

A retrospective review was performed looking at over 100 consecutive primary pharyngoplasty operations for velopharyngeal dysfunction over a 10-year period at a single institution. Aetiology, peri-operative course and speech outcomes for the cohort between January 2010 through January 2020 were assessed. A comprehensive literature review was performed for comparison and analysis of the studies' data.

RESULTS

Ninety-seven consecutive patients were included in the study on which 103 operations were performed. Average age at time of surgery was 7.25 years old. Approximately 37% of the patients had a diagnosed syndrome, sequence or chromosomal abnormality. Ninety-seven of the 103 operations were primary pharyngoplasties, 4 were revision pharyngoplasties and 2 return to theatre procedures. Regarding speech outcomes, 51% of the patients that had formal speech assessments were found to have a significant improvement, 42% moderate improvement and 7% had no improvement. 93% of the patients that underwent pharyngoplasty in this study had significant or moderate improvement in speech outcomes. These speech outcomes and post-operative complications such as obstructive sleep apnoea are analysed.

CONCLUSION

This study demonstrates that pharyngoplasty is a safe procedure for velopharyngeal insufficiency with a good overall success rate. The major outcomes assessed including complications & safety, revision rate and speech outcomes are comparative to previous international studies.

摘要

背景

腭咽闭合不全是腭裂手术中常见的问题,咽成形术是主要的手术治疗方法。在本研究中,我们旨在调查单一机构的经验的适应症和结果,并与国际文献进行比较。

方法

对单一机构在10年期间连续进行的100多例原发性咽成形术治疗腭咽功能障碍的病例进行回顾性研究。评估了2010年1月至2020年1月该队列的病因、围手术期过程和语音结果。进行了全面的文献综述,以比较和分析研究数据。

结果

该研究纳入了97例连续患者,共进行了103次手术。手术时的平均年龄为7.25岁。约37%的患者被诊断患有综合征、序列或染色体异常。103例手术中,97例为原发性咽成形术,4例为翻修咽成形术,2例为再次手术。关于语音结果,在接受正式语音评估的患者中,51%有显著改善,42%有中度改善,7%无改善。本研究中接受咽成形术的患者中有93%在语音结果方面有显著或中度改善。分析了这些语音结果和术后并发症,如阻塞性睡眠呼吸暂停。

结论

本研究表明,咽成形术是治疗腭咽闭合不全的一种安全手术,总体成功率较高。评估的主要结果包括并发症和安全性、翻修率和语音结果,与以往的国际研究相比具有可比性。

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