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经胸腔内注射鸦胆子油乳剂为胸膜间皮瘤恶性胸腔积液患者带来长期获益:一例报告。

Intrapleural injection of brucea javanica oil emulsion provided a long-term benefits in patient with malignant pleural effusion from pleural mesothelioma: A case report.

机构信息

Department of Oncology of Yue Yang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine.

Department of Oncology of Yue Yang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine.

出版信息

Explore (NY). 2024 Jan-Feb;20(1):126-129. doi: 10.1016/j.explore.2023.06.001. Epub 2023 Jun 2.

Abstract

Malignant pleural mesothelioma (MPM) is a severe form of cancer that originates from mesothelium cells. Around 54-90% of mesotheliomas are associated with pleural effusions. Brucea Javanica Oil Emulsion (BJOE) is the processed oil derived from the seeds of Brucea javanica, which has shown potential as a treatment option for several types of cancer. Here, we present a case study of a MPM patient with malignant pleural effusion who received intrapleural injection of BJOE. The treatment resulted in the complete response of pleural effusion and chest tightness. While the precise mechanisms underlying the therapeutic effects of BJOE for pleural effusion are not yet fully understood, it has demonstrated a satisfactory clinical response without significant adverse effects.

摘要

恶性胸膜间皮瘤(MPM)是一种起源于间皮细胞的严重癌症。约 54-90%的间皮瘤与胸腔积液有关。鸦胆子油乳是从鸦胆子中提取的加工油,已显示出作为几种癌症治疗选择的潜力。在这里,我们报告了一例接受鸦胆子油乳胸腔内注射的恶性胸腔积液 MPM 患者的病例研究。该治疗导致胸腔积液和胸闷完全缓解。虽然鸦胆子油乳治疗胸腔积液的确切机制尚不完全清楚,但它已显示出令人满意的临床反应,且没有明显的不良反应。

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