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CyberKnife 立体定向放射手术治疗难治性双侧三叉神经痛。病例报告。

CyberKnife Radiosurgery for refractory bilateral trigeminal neuralgia. Case report.

机构信息

Universidad de Sucre, Facultad Ciencias de la Salud, Grupo de Ciencias Médicas y Farmacéuticas. Sincelejo, Colombia.

Clínica Las Peñitas, Sincelejo, Colombia.

出版信息

Colomb Med (Cali). 2022 Dec 30;53(4):e5005283. doi: 10.25100/cm.v53i4.5283. eCollection 2022 Oct-Dec.

Abstract

UNLABELLED

Case description: A case of a 37-year-old female patient suffering from refractory bilateral trigeminal neuralgia is presented, who underwent various interventions such as acupuncture, block therapies and even microvascular decompression without effective pain relief.

CLINICAL FINDINGS

Paresthesias and shooting-like twinges of pain intensity 10/10 in bilateral maxillary and mandibular branches of the trigeminal nerve, with nasal and intraoral triggers that made eating impossible, becoming increasingly severe since refractoriness to microvascular decompression and carbamazepines, triggering the twinges even during sleep, generating somnolence, depressive mood and social isolation.

TREATMENT AND RESULTS

The patient was evaluated by an interdisciplinary neuro-oncology team, where, in accordance with the analysis of the brain magnetic resonance imaging and the patient's history, it was indicated to perform Cyberknife® radiosurgery in monofraction on the left trigeminal and subsequently treat the contralateral trigeminal. When treated with Cyberknife® radiosurgery, the patient reported absolute improvement in her pain for 2 years.

CLINICAL RELEVANCE

Radiosurgery by CyberKnife is not yet the first line of management in trigeminal neuralgia, however, it should be considered since several studies have managed to demonstrate an increase in the quality of life of patients and pain relief in refractory or severe cases. of said pathology.

摘要

未注明

病例描述:一位 37 岁的女性患者,患有难治性双侧三叉神经痛,她经历了各种干预措施,如针灸、阻滞疗法,甚至微血管减压术,但都没有有效缓解疼痛。

临床发现

双侧上颌和下颌三叉神经分支出现感觉异常和剧烈刺痛,强度为 10/10,有鼻内和口腔内触发因素,使进食变得不可能,自微血管减压和卡马西平耐药以来,疼痛越来越严重,甚至在睡眠中也会引发刺痛,导致嗜睡、抑郁情绪和社交隔离。

治疗和结果

该患者由神经肿瘤多学科团队进行评估,根据脑磁共振成像和患者病史分析,建议对左侧三叉神经进行 Cyberknife®单次分割放射外科手术,随后对对侧三叉神经进行治疗。当接受 Cyberknife®放射外科手术治疗时,患者报告疼痛绝对改善了 2 年。

临床意义

CyberKnife 放射外科手术并非三叉神经痛的一线治疗方法,但由于多项研究成功证明了它可以提高难治性或严重三叉神经痛患者的生活质量并缓解疼痛,因此应考虑使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f573/10243136/a55e18c05db4/1657-9534-cm-53-04-e5005283-gf1.jpg

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