Lazaro Johnlevi S, Lutz Rex, Deirmengian Gregory K
Orthopedic Surgery, Jefferson Health New Jersey, Stratford, USA.
Orthopaedic Surgery, Rothman Orthopaedic Institute, Philadelphia, USA.
Cureus. 2023 May 5;15(5):e38597. doi: 10.7759/cureus.38597. eCollection 2023 May.
Alkaptonuria (AKU) is a rare hereditary disorder of tyrosine degradation. The disorder is characterized by the accumulation of a pigment called homogentisic acid. Its accumulation can lead to the breakdown of connective tissue, including tendons. This report presents a 46-year-old male with a history of bilateral total knee arthroplasty (TKA) who sustained bilateral patellar tendon rupture after an acute injury. A single-stage bilateral knee revision with direct repair of the extensor mechanism augmented with Achilles allograft was performed. The procedure was successful, and the patient had an excellent post-operative outcome at one year post-operatively. This case attempts to highlight the possible complications from AKU in order to better counsel patients with this condition who are undergoing TKA.
黑尿症（AKU）是一种罕见的酪氨酸降解遗传性疾病。该疾病的特征是一种名为尿黑酸的色素积累。其积累会导致包括肌腱在内的结缔组织分解。本报告介绍了一名46岁男性，有双侧全膝关节置换术（TKA）病史，在急性损伤后发生双侧髌腱断裂。进行了一期双侧膝关节翻修术，直接修复伸肌机制，并使用同种异体跟腱加强。手术成功，患者术后一年的结果极佳。本病例旨在强调AKU可能引发的并发症，以便更好地为接受TKA的该疾病患者提供咨询。
