Department of Anesthesiology, Division of Pediatric Anesthesiology, St. Louis Children's Hospital, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Pediatr Transplant. 2023 Sep;27(6):e14558. doi: 10.1111/petr.14558. Epub 2023 Jun 8.
Regional anesthesia allows for opioid-sparing and enhanced recovery after many major surgeries. Erector spinae blockade, with reduced bleeding risk and the option for continuous infusion, offers an opportunity to promote this principle in pediatric liver transplant patients. Our goal was to evaluate pain scores, opioid use, and return of bowel function following continuous ESP blockade in pediatric liver transplant recipients.
This retrospective cohort study included extubated patients who received a liver transplant at St. Louis Children's Hospital from July 2016 to July 2021. The control group, which did not meet the criteria for ESP blockade and received standard analgesia regimens, was compared to the group receiving continuous ESP blockade. Measured outcomes included pain scores, opioid consumption through postoperative day two, date of first bowel movement, and length of stay in the ICU and the hospital.
Patient demographics between control and ESP groups showed no significant differences. Pain scores between control and ESP groups also showed no significant differences. Intraoperative and postoperative opioid requirements, studied in oral morphine equivalents per kilogram (OME/kg), were significantly lower for patients with ESP blockade. Time to first bowel movement was also significantly earlier for the ESP group. No significant differences were found in length of ICU or hospital stay. There were no safety concerns or complications related to ESP blockade.
Use of continuous ESP blockade resulted in reduced opioid consumption through postoperative day two and earlier return of bowel function.
区域麻醉可减少许多大手术后的阿片类药物使用并促进术后恢复。竖脊肌阻滞术具有降低出血风险和连续输注的选择,为在小儿肝移植患者中推广这一原则提供了机会。我们的目标是评估连续竖脊肌阻滞术在小儿肝移植受者中的疼痛评分、阿片类药物使用情况和肠功能恢复情况。
本回顾性队列研究纳入了 2016 年 7 月至 2021 年 7 月在圣路易斯儿童医院接受肝移植的气管拔管患者。与接受标准镇痛方案但不符合竖脊肌阻滞术标准的对照组相比,评估了接受连续竖脊肌阻滞术的组。测量的结果包括疼痛评分、术后两天内的阿片类药物使用量、首次肠蠕动时间以及 ICU 和医院的住院时间。
对照组和竖脊肌阻滞组患者的人口统计学特征无显著差异。两组之间的疼痛评分也无显著差异。接受竖脊肌阻滞术的患者术中及术后的阿片类药物需求(以每公斤口服吗啡当量(OME/kg)表示)明显较低。竖脊肌阻滞组的首次肠蠕动时间也明显更早。ICU 和医院的住院时间无显著差异。连续竖脊肌阻滞术无安全性问题或相关并发症。
使用连续竖脊肌阻滞术可减少术后两天内的阿片类药物使用量并更早恢复肠功能。