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行慢性血栓栓塞性肺动脉高压患者安全有效的球囊肺血管成形术的技术考虑因素。

Technical Considerations for Performing Safe and Effective Balloon Pulmonary Angioplasty in Patients with Chronic Thromboembolic Pulmonary Hypertension.

机构信息

Faculty of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582, Japan.

Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582, Japan.

出版信息

Interv Cardiol Clin. 2023 Jul;12(3):367-380. doi: 10.1016/j.iccl.2023.02.003. Epub 2023 Mar 15.

Abstract

Chronic thromboembolic pulmonary hypertension (CTEPH) is a late complication of acute pulmonary thromboembolism owing to incomplete clot dissolution in pulmonary artery. Pulmonary endarterectomy is the first-line treatment for CTEPH. However, 40% of patients are not candidates for surgery because of distal lesions or age. Balloon pulmonary angioplasty (BPA), a catheter-based intervention, is increasingly being used worldwide for treating inoperable CTEPH. Previous BPA strategy had a major concern of reperfusion pulmonary edema as a complication. However, recent refined strategies promise safe and effective BPA. Five-year survival rate after BPA is 90% for inoperable CTEPH, comparable with that of operable CTEPH.

摘要

慢性血栓栓塞性肺动脉高压(CTEPH)是急性肺血栓栓塞症的一种晚期并发症,由于肺动脉内血栓不完全溶解所致。肺动脉内膜切除术是 CTEPH 的一线治疗方法。然而,由于存在远端病变或年龄等因素,40%的患者不适合手术。球囊肺动脉成形术(BPA)作为一种基于导管的介入治疗方法,在全球范围内越来越多地用于治疗无法手术的 CTEPH。以前的 BPA 策略主要关注再灌注肺水肿作为一种并发症。然而,最近的改良策略保证了 BPA 的安全性和有效性。对于无法手术的 CTEPH,BPA 后的 5 年生存率为 90%,与可手术的 CTEPH 相当。

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