Aronis John M, Ye Ye, Espino Jessi, Hochheiser Harry, Michaels Marian G, Cooper Gregory F
medRxiv. 2023 May 16:2023.05.10.23289799. doi: 10.1101/2023.05.10.23289799.
It would be highly desirable to have a tool that detects the outbreak of a new influenza-like illness, such as COVID-19, accurately and early. This paper describes the algorithm that first models the daily occurrence of a set of known influenza-like illnesses in a hospital emergency department using findings extracted from patient-care reports using natural language processing. We include results based on modeling the diseases influenza, respiratory syncytial virus, human metapneumovirus, and parainfluenza for five emergency departments in Allegheny County Pennsylvania from June 1, 2010 through May 31, 2015. We then show how the algorithm can be extended to detect the presence of an unmodeled disease which may represent a novel disease outbreak. We also include results for detecting an outbreak of an unmodeled disease during the mentioned time period, which in retrospect was very likely an outbreak of Enterovirus D68.
非常希望能有一个工具,能够准确且早期地检测出新型流感样疾病(如COVID-19)的爆发。本文描述了一种算法,该算法首先使用自然语言处理从患者护理报告中提取的结果,对医院急诊科一组已知流感样疾病的每日发病情况进行建模。我们给出了2010年6月1日至2015年5月31日期间宾夕法尼亚州阿勒格尼县五个急诊科对流感、呼吸道合胞病毒、人偏肺病毒和副流感进行建模的结果。然后,我们展示了该算法如何扩展以检测可能代表新型疾病爆发的未建模疾病的存在。我们还给出了在上述时间段内检测未建模疾病爆发的结果,事后看来很可能是肠道病毒D68的爆发。