南非有和无宫内人类免疫缺陷病毒暴露的儿童中 T 细胞斑点试验的反应性。
T-SPOT.TB Reactivity in Southern African Children With and Without in Utero Human Immunodeficiency Virus Exposure.
机构信息
Division of Immunology, Department of Pathology, University of Cape Town, Cape Town, South Africa.
Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
出版信息
Clin Infect Dis. 2023 Oct 13;77(8):1133-1136. doi: 10.1093/cid/ciad356.
Abstract
Infants who are human immunodeficiency virus (HIV)-exposed uninfected (iHEU) experience higher risk of infectious morbidity than infants HIV-unexposed uninfected (iHUU). We compared tuberculosis (TB) infection prevalence in 418 Bacillus Calmette-Guérin vaccinated sub-Saharan African iHEU and iHUU aged 9-18 months using T-SPOT.TB. Prevalence of TB infection was low and did not differ by HIV exposure status.
摘要
HIV 暴露未感染婴儿（iHEU）比 HIV 未暴露未感染婴儿（iHUU）有更高的传染性发病风险。我们使用 T-SPOT.TB 比较了 418 名接种卡介苗的撒哈拉以南非洲地区 9-18 月龄 iHEU 和 iHUU 中结核（TB）感染的流行率。TB 感染的流行率较低，且与 HIV 暴露状态无关。
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