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经体动脉干修复术的婴儿行胃造口术和气管造口术的结果:使用儿科健康信息系统的数据库研究。

Outcomes of Gastrostomy and Tracheostomy in Infants Undergoing Truncus Arteriosus Repair: Database Study Using the Pediatric Health Information System.

机构信息

Division of Pediatric Cardiology, Department of Pediatrics, Medical University of South Carolina College of Medicine, Charleston, SC.

Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.

出版信息

Pediatr Crit Care Med. 2023 Nov 1;24(11):e540-e546. doi: 10.1097/PCC.0000000000003295. Epub 2023 Jun 9.

Abstract

OBJECTIVES

We sought to determine the prevalence of and factors associated with gastrostomy tube placement and tracheostomy in infants undergoing truncus arteriosus repair, and associations between these procedures and outcome.

DESIGN

Retrospective cohort study.

SETTING

Pediatric Health Information System database.

PATIENTS

Infants less than 90 days old who underwent truncus arteriosus repair from 2004 to 2019.

INTERVENTIONS

None.

MEASUREMENTS AND MAIN RESULTS

Multivariable logistic regression models were used to identify factors associated with gastrostomy tube and tracheostomy placement and to identify associations between these procedures and hospital mortality and prolonged postoperative length of stay (LOS; > 30 d). Of 1,645 subjects, gastrostomy tube was performed in 196 (11.9%) and tracheostomy in 56 (3.4%). Factors independently associated with gastrostomy tube placement were DiGeorge syndrome, congenital airway anomaly, admission age less than or equal to 2 days, vocal cord paralysis, cardiac catheterization, infection, and failure to thrive. Factors independently associated with tracheostomy congenital airway anomaly, truncal valve surgery, and cardiac catheterization. Gastrostomy tube was independently associated with prolonged postoperative LOS (odds ratio [OR], 12.10; 95% CI, 7.37-19.86). Hospital mortality occurred in 17 of 56 patients (30.4%) who underwent tracheostomy versus 147 of 1,589 patients (9.3%) who did not ( p < 0.001), and median postoperative LOS was 148 days in patients who underwent tracheostomy versus 18 days in those who did not ( p < 0.001). Tracheostomy was independently associated with mortality (OR, 3.11; 95% CI, 1.43-6.77) and prolonged postoperative LOS (OR, 9.85; 95% CI, 2.16-44.80).

CONCLUSIONS

In infants undergoing truncus arteriosus repair, tracheostomy is associated with greater odds of mortality; while gastrostomy and tracheostomy are strongly associated with greater odds of prolonged postoperative LOS.

摘要

目的

我们旨在确定接受动脉干修复术的婴儿行胃造口术和气管切开术的流行率及相关因素,并确定这些操作与结局之间的关系。

设计

回顾性队列研究。

设置

儿科健康信息系统数据库。

患者

2004 年至 2019 年期间接受动脉干修复术的 90 天以下的婴儿。

干预

无。

测量和主要结果

采用多变量逻辑回归模型确定与胃造口术和气管切开术相关的因素,并确定这些操作与院内死亡率和术后住院时间延长(>30 d)之间的关系。在 1645 名患者中,196 名(11.9%)患者进行了胃造口术,56 名(3.4%)患者进行了气管切开术。胃造口术独立相关的因素为 DiGeorge 综合征、先天性气道异常、入院年龄≤2 天、声带麻痹、心导管检查、感染和生长迟缓。气管切开术独立相关的因素为先天性气道异常、干瓣手术和心导管检查。胃造口术与术后住院时间延长独立相关(比值比[OR],12.10;95%置信区间[CI],7.37-19.86)。在接受气管切开术的 56 名患者中,有 17 例(30.4%)发生院内死亡,而在未接受气管切开术的 1589 名患者中,有 147 例(9.3%)发生院内死亡(p<0.001),接受气管切开术的患者术后住院时间中位数为 148 天,而未接受气管切开术的患者为 18 天(p<0.001)。气管切开术与死亡率(OR,3.11;95%CI,1.43-6.77)和术后住院时间延长(OR,9.85;95%CI,2.16-44.80)独立相关。

结论

在接受动脉干修复术的婴儿中,气管切开术与更高的死亡率相关;而胃造口术和气管切开术与术后住院时间延长的风险显著增加相关。

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