Donald P. and Katherine B. Loker Hydrocarbon Institute, Department of Chemistry, and Wrigley Institute for Environmental Studies, University of Southern California, Los Angeles, California 90089-1661, USA.
Chem Commun (Camb). 2023 Jun 27;59(52):8107-8110. doi: 10.1039/d3cc01014g.
We report two bifunctional (pyridyl)carbene-iridium(I) complexes that catalyze ketone and aldehyde hydrogenation at ambient pressure. Aryl, heteroaryl, and alkyl groups are demonstrated, and mechanistic studies reveal an unusual polarization effect in which the rate is dependant of proton, rather than hydride, transfer. This method introduces a convenient, waste-free alternative to traditional borohydride and aluminum hydride reagents.
我们报告了两个双功能（吡啶基）卡宾-铱（I）配合物，它们在环境压力下催化酮和醛的氢化。芳基、杂芳基和烷基都得到了证明，并且机理研究揭示了一种不寻常的极化效应，其中速率取决于质子，而不是氢化物转移。这种方法为传统的硼氢化钠和氢化铝试剂提供了一种方便、无废物的替代方法。
