Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, United States of America.
Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, United States of America.
Theor Popul Biol. 2023 Oct;153:50-68. doi: 10.1016/j.tpb.2023.05.001. Epub 2023 Jun 7.
Research shows that geographic disparities in life expectancy between leading and lagging states are increasing over time while racial disparities between Black and White Americans have been going down. In the 65+ age strata morbidity is the most common cause of death, making differences in morbidity and associated adverse health-related outcomes between advantaged and disadvantaged groups an important aspect of disparities in life expectancy at age 65 (LE65). In this study, we used Pollard's decomposition to evaluate the disease-related contributions to disparities in LE65 for two types of data with distinctly differing structures: population/registry and administrative claims. To do so, we analyzed Pollard's integral, which is exact by construction, and developed exact analytic solutions for both types of data without the need for numerical integration. The solutions are broadly applicable and easily implemented. Applying these solutions, we found that the largest relative contributions to geographic disparities in LE65 were chronic lower respiratory diseases, circulatory diseases, and lung cancer; and, to racial disparities: arterial hypertension, diabetes mellitus, and cerebrovascular diseases. Overall, the increase in LE65 observed over 1998-2005 and 2010-2017 was primarily due to a reduction in the contributions of acute and chronic ischemic diseases; this was partially offset by increased contributions of diseases of the nervous system including dementia and Alzheimer's disease.
研究表明,随着时间的推移,领先州和落后州之间预期寿命的地理差距在不断扩大,而美国黑人和白人之间的种族差距一直在缩小。在 65 岁以上的年龄段,发病率是最常见的死亡原因,因此,优势群体和弱势群体之间发病率的差异以及与发病率相关的不良健康相关结果差异,是 65 岁时预期寿命差异的一个重要方面。在这项研究中,我们使用 Pollard 分解法评估了两种结构明显不同的数据类型中与疾病相关的差异对 LE65 的贡献:人群/登记和行政索赔。为此,我们分析了 Pollard 积分,该积分通过构造是精确的,并为这两种数据类型开发了精确的解析解,而无需数值积分。这些解决方案具有广泛的适用性且易于实现。应用这些解决方案,我们发现,导致 LE65 地理差异的最大相对贡献是慢性下呼吸道疾病、循环系统疾病和肺癌;而导致种族差异的主要因素是:动脉高血压、糖尿病和脑血管疾病。总体而言,1998-2005 年和 2010-2017 年间 LE65 的增长主要归因于急性和慢性缺血性疾病的减少;而这一趋势部分被包括痴呆症和阿尔茨海默病在内的神经系统疾病的发病率增加所抵消。