Lops Diego, Romeo Eugenio, Mensi Magda, Troiano Giuseppe, Zhurakivska Khrystyna, Del Fabbro Massimo, Palazzolo Antonino
Department of Biomedical, Surgical and Dental Sciences, Dental Clinic, School of Dentistry, University of Milan, 20122 Milan, Italy.
Department of Surgical Specialties, Radiological Science and Public Health, University of Brescia, 25123 Brescia, Italy.
J Clin Med. 2023 Jun 4;12(11):3847. doi: 10.3390/jcm12113847.
Computer-aided design and computer-aided manufacturing customized abutments are increasingly used in everyday clinical practice. Nevertheless, solid scientific evidence is currently lacking regarding their potential advantages in terms of soft tissue stability. The main aim of this systematic review and meta-analysis was to compare the soft tissue outcomes of prefabricated versus customized (CAD/CAM) abutments. The present review was registered with PROSPERO (CRD42020161875) and the protocol was developed according to the PRISMA statement. An electronic search was performed on three databases (PubMed, Embase and Cochrane Central) up to May 2023. Data extraction was followed by qualitative and quantitative analysis of the included studies. Three randomized controlled clinical trials and three controlled clinical trials (number of patients = 230; number of dental implants = 230) with a follow-up of between 12 and 36 months were included. No significant differences were observed between prefabricated versus customized (CAD/CAM) abutments regarding midfacial mucosal recession, interproximal papillae and pink aesthetic score (PES) after 12 months. Conclusion: The potential benefits of CAD/CAM abutments on soft tissues should be better clarified in future investigations. The usage of customized CAD/CAM abutments in everyday clinical practice should be based on a careful case-by-case evaluation (CRD42020161875).
计算机辅助设计和计算机辅助制造定制基台在日常临床实践中越来越常用。然而，目前缺乏关于其在软组织稳定性方面潜在优势的确凿科学证据。本系统评价和荟萃分析的主要目的是比较预制基台与定制（CAD/CAM）基台的软组织结果。本评价已在PROSPERO（CRD42020161875）注册，方案根据PRISMA声明制定。截至2023年5月，在三个数据库（PubMed、Embase和Cochrane Central）上进行了电子检索。数据提取后对纳入研究进行定性和定量分析。纳入了三项随机对照临床试验和三项对照临床试验（患者数量 = 230；牙种植体数量 = 230），随访时间为12至36个月。12个月后，预制基台与定制（CAD/CAM）基台在面部中部黏膜退缩、邻间乳头和粉色美学评分（PES）方面未观察到显著差异。结论：CAD/CAM基台对软组织的潜在益处应在未来研究中得到更好的阐明。日常临床实践中定制CAD/CAM基台的使用应基于仔细的逐例评估（CRD42020161875）。
