McCormack Sean, Hamad Eyad, Hamad Amar
Saint James School of Medicine, Cane Hall Road, Arnos Vale, Saint Vincent and the Grenadines.
Northwestern School of Medicine, 10604 SW Hwy Ste 200, Chicago Ridge, IL 60415, USA.
Case Rep Hematol. 2023 Jun 3;2023:9622042. doi: 10.1155/2023/9622042. eCollection 2023.
Plasmacytoma is a rare cancer that originates from a single plasma cell and is characterized by the abnormal proliferation of monoclonal plasma cells. It is typically localized in a single area of the body, most commonly in the bone or soft tissue. Solitary plasmacytoma can be further classified as either solitary plasmacytoma of bone (SPB) or solitary extramedullary plasmacytoma (SEP or EMP). Diagnosis may be delayed in symptomatically silent plasmacytomas, but early diagnosis and prompt treatment are crucial for the management of this disease. The mean age for patients with plasmacytoma varies depending on the specific type of plasmacytoma, but generally, it is more common in older adults. Soft tissue plasmacytomas are uncommon, and plasmacytomas manifesting within the breast are extremely rare, especially when they are not a manifestation of multiple myeloma (MM). This report presents a case of SEP of the breast in a 79-year-old female patient. This rare disease needs to be studied further in terms of long-term survival and disease progression to MM. By raising awareness and understanding of plasmacytoma, we aim to improve outcomes and quality of life for patients affected by this disease.
浆细胞瘤是一种罕见的癌症,起源于单个浆细胞,其特征是单克隆浆细胞异常增殖。它通常局限于身体的单个部位,最常见于骨骼或软组织。孤立性浆细胞瘤可进一步分为骨孤立性浆细胞瘤(SPB)或孤立性髓外浆细胞瘤(SEP或EMP)。有症状但无症状的浆细胞瘤的诊断可能会延迟,但早期诊断和及时治疗对于这种疾病的管理至关重要。浆细胞瘤患者的平均年龄因浆细胞瘤的具体类型而异,但一般来说,在老年人中更为常见。软组织浆细胞瘤不常见,乳腺内出现的浆细胞瘤极为罕见,尤其是当它们不是多发性骨髓瘤(MM)的表现时。本报告介绍了一名79岁女性患者的乳腺SEP病例。这种罕见疾病在长期生存和向MM的疾病进展方面需要进一步研究。通过提高对浆细胞瘤的认识和理解我们旨在改善受这种疾病影响的患者的治疗效果和生活质量。