Department of Radiology, UC Davis Health, Sacramento, California, USA.
Department of Pathology and Laboratory Medicine, UC Davis Health, Sacramento, California, USA.
J Radiol Case Rep. 2020 Dec 31;14(12):14-23. doi: 10.3941/jrcr.v14i12.4110. eCollection 2020 Dec.
Extramedullary plasmacytoma of the breast is rare. It is important to recognize the imaging findings and include it as a differential consideration in multiple myeloma patients with a breast mass. A 74-year-old woman undergoing chemotherapy for relapsed multiple myeloma presented with a palpable mass in her right breast. A screening mammogram four months prior was unremarkable. She underwent a diagnostic right mammogram which showed two well-circumscribed hyperdense masses. An ultrasound of the right breast showed mixed echogenic masses with indistinct margins and increased vascularity. Ultrasound guided biopsy confirmed the presence of an extramedullary plasmacytoma. A follow-up whole body PET/CT demonstrated an FDG-avid right breast mass with extensive osseous metastases.
乳腺髓外浆细胞瘤较为罕见。对于正在接受多发性骨髓瘤化疗的患者，如果其乳房内出现肿块，我们需要识别其影像学表现并将其作为鉴别诊断的考虑因素之一。一名 74 岁女性，因复发性多发性骨髓瘤正在接受化疗，其右侧乳房出现可触及的肿块。四个月前的筛查性乳房 X 线摄影术未见异常。她进行了右侧乳腺的诊断性乳房 X 线摄影术，结果显示两个边界清楚的高密度肿块。右侧乳腺超声显示混杂回声肿块，边界模糊，血流增加。超声引导下活检证实存在髓外浆细胞瘤。后续的全身 PET/CT 显示 FDG 摄取的右侧乳腺肿块，并伴有广泛的骨转移。
