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白内障患者前囊抛光的疗效与安全性:一项荟萃分析

Efficacy and safety of anterior capsule polishing in cataract patients: a meta-analysis.

作者信息

Liu Beichen, Zhang Lijun, Fang Shifeng

机构信息

Ophthalmology Department, The Third People's Hospital of Dalian Dalian 116033, Liaoning, China.

出版信息

Am J Transl Res. 2023 May 15;15(5):3662-3673. eCollection 2023.

Abstract

OBJECTIVE

This research summarizes and analyzes the effects of polishing of the anterior capsule (PAC) on visual function, maintenance of effective lens position (ELP), and postoperative complications in various studies, so as to determine whether PAC can be used to improve the surgical outcome of cataracts.

METHODS

The literature related to PAC published before June 2022 was searched in PubMed, Web of Science, EMBASE, Cochrane, Google, Wanfang, Weipu and CNKI databases. Changes in visual function [uncorrected visual acuity (UCVA) and spherical equivalent refraction (SER)], effective lens position (ELP), and postoperative complications [anterior capsular opacification (ACO) and posterior capsular opacification (PCO)] in the PAC intervention group were summarized and analyzed, and the standardized mean difference (SMD) or odds ratio (OR) with 95% CI was calculated by Review Manager 5.3.

RESULTS

By screening the literature, this meta-analysis finally included 10 studies with 2,639 eyes. The UCVA of patients was significantly improved in the PAC intervention group, while the root mean square of ELP (ELP) level and ACO incidence decreased. In addition, PAC did not obviously reduce the incidence of PCO after cataract surgery.

CONCLUSION

PAC can effectively maintain the axial stability of the implanted lens and reduce the possibility of developing ACO, thus improving patients' visual function, which can effectively improve both the efficacy and safety of cataract surgery.

摘要

目的

本研究总结并分析了不同研究中前囊抛光(PAC)对视觉功能、有效晶状体位置(ELP)维持及术后并发症的影响,以确定PAC是否可用于改善白内障手术效果。

方法

在PubMed、Web of Science、EMBASE、Cochrane、Google、万方、维普和知网数据库中检索2022年6月前发表的与PAC相关的文献。总结并分析PAC干预组视觉功能[未矫正视力(UCVA)和等效球镜度(SER)]、有效晶状体位置(ELP)及术后并发症[前囊混浊(ACO)和后囊混浊(PCO)]的变化,采用RevMan 5.3计算标准化均数差(SMD)或比值比(OR)及95%可信区间。

结果

通过文献筛选,本荟萃分析最终纳入10项研究共2639只眼。PAC干预组患者的UCVA显著提高,同时ELP水平的均方根及ACO发生率降低。此外,PAC对白内障手术后PCO的发生率无明显降低作用。

结论

PAC可有效维持植入晶状体的轴向稳定性,降低发生ACO的可能性,从而改善患者视觉功能,可有效提高白内障手术的疗效和安全性。

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