Wu Zhizhong, Zhang Baoyue, Chen Zhimin, Liu Caijuan
Hebei Provincial Key Laboratory of Ophthalmology, Department of Ophthalmology, Hebei Eye Hospital, Xingtai, Hebei Province, China.
Sci Rep. 2025 May 20;15(1):17422. doi: 10.1038/s41598-025-02573-z.
To report the indications and outcomes of intraocular lens (IOL) exchange at a tertiary referral center in northern China over a period of 8 years. Setting: Ophthalmology departments of Hebei Eye Hospital, Hebei, China. Design: Retrospective cross-sectional study. In this retrospective study, the medical records of 233 patients with a history of IOL exchange were reviewed between 2016 and 2024. These cases were reviewed to determine surgical indications, the type of intraocular lens removed, the type of intraocular lens implanted, the time between operations, surgical complications, and visual outcomes. All postoperative data were analyzed at least six months after follow-up. The mean age of our participants was 50.05 ± 21.76 years (range 5-82 years), with a male percentage of 65.67%. The mean time between primary surgery and IOL exchange was 6.64 ± 6.16years (range 0.01-30 year). The main indications of IOL exchange were IOL dislocation (63.37%) and IOL opacification (21.81%). The most common ophthalmic comorbidity was high myopia. Procedures for secondary IOL implantation were scleral fixated IOL with sutures (34.16%), IOL in ciliary sulcus (26.75%), in-the-bag IOL (26.31%) and Iris fixation IOL (7.82%). The mean postoperative corrected distance visual acuity (CDVA) was significantly higher compared to the mean preoperative CDVA (p = 0.00). The mean preoperative and postoperative IOP were 16.23 ± 4.92 and 14.84 ± 3.05 mmHg, respectively (p = 0.00). No serious complications ware observed. IOL dislocation is the most common indication of intraocular lens implantation, followed by IOL opacification. Simultaneous scleral-sutured fixation after IOL replacement is the most common procedure in secondary IOL implantation.
报告中国北方一家三级转诊中心8年间人工晶状体（IOL）置换的适应证及结果。地点：中国河北省河北眼科医院眼科。设计：回顾性横断面研究。在这项回顾性研究中，对2016年至2024年间233例有IOL置换史患者的病历进行了回顾。对这些病例进行审查以确定手术适应证、取出的人工晶状体类型、植入的人工晶状体类型、手术间隔时间、手术并发症和视力结果。所有术后数据在随访至少6个月后进行分析。参与者的平均年龄为50.05±21.76岁（范围5 - 82岁），男性占比65.67%。初次手术与IOL置换之间的平均时间为6.64±6.16年（范围0.01 - 30年）。IOL置换的主要适应证为IOL脱位（63.37%）和IOL混浊（21.81%）。最常见的眼科合并症是高度近视。二期IOL植入手术方式为巩膜缝线固定IOL（34.16%）、睫状沟IOL（26.75%）、囊袋内IOL（26.31%）和虹膜固定IOL（7.82%）。术后平均矫正远视力（CDVA）显著高于术前平均CDVA（p = 0.00）。术前和术后平均眼压分别为16.23±4.92和14.84±3.05 mmHg（p = 0.00）。未观察到严重并发症。IOL脱位是人工晶状体植入最常见的适应证，其次是IOL混浊。IOL置换后同时进行巩膜缝线固定是二期IOL植入最常见的手术方式。
