Lee Wonsup, Park Jun-Beom
Department of Prosthodontics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, 06591, Republic of Korea.
Department of Periodontics, College of Medicine, The Catholic University of Korea, Seoul, 06591, Republic of Korea.
Heliyon. 2023 May 2;9(5):e15859. doi: 10.1016/j.heliyon.2023.e15859. eCollection 2023 May.
Peri-implantitis poses an imminent challenge to the field of implant dentistry. Considering the promising findings of sodium hypochlorite and periodontal lesions, the aim of the present study was to evaluate the clinical effects of sodium hypochlorite oral rinse on peri-implantitis lesions. Twelve peri-implantitis patients were instructed to rinse with 15 mL of a fresh solution of 0.25% sodium hypochlorite for 30 s twice a week for 3 months. At baseline and 3-month visits, probing depth and modified sulcular bleeding index were recorded at 6 points per lesion (mesiobuccal, buccal, distobuccal, mesiolingual, lingual, and distolingual). Individual and total bacterial loads of 18 pre-designated species of microorganisms were analyzed by real-time PCR methods. Probing depth decreased after the experiment, with an average difference of 1.1 mm and a standard deviation of 1.7 mm. The modified sulcular bleeding index decreased by a mean value of 0.8 with a standard deviation of 1.1. This study demonstrated the clinical effects of sodium hypochlorite oral rinse on peri-implantitis lesions and the reduction of periodontal probing depth and gingival bleeding index. This study suggested that the concentration of 0.25% be used for treatment of peri-implantitis.
种植体周围炎对种植牙科领域构成了紧迫的挑战。鉴于次氯酸钠与牙周病变的相关研究成果令人鼓舞，本研究旨在评估次氯酸钠口腔含漱液对种植体周围炎病变的临床效果。12名种植体周围炎患者被要求每周两次用15毫升0.25%次氯酸钠新鲜溶液含漱30秒，持续3个月。在基线和3个月复诊时，记录每个病变6个位点（近中颊侧、颊侧、远中颊侧、近中舌侧、舌侧和远中舌侧）的探诊深度和改良龈沟出血指数。通过实时聚合酶链反应方法分析18种预先指定的微生物的个体和总细菌载量。实验后探诊深度降低，平均差值为1.1毫米，标准差为1.7毫米。改良龈沟出血指数平均降低0.8，标准差为1.1。本研究证明了次氯酸钠口腔含漱液对种植体周围炎病变的临床效果以及牙周探诊深度和牙龈出血指数的降低。本研究表明0.25%的浓度可用于治疗种植体周围炎。
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