中高危急性肺栓塞患者的真实世界特征和结局。
Real-world characteristics and outcomes of patients with intermediate high risk acute pulmonary embolism.
机构信息
Department of Internal Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Cardiovascular Sciences, The Netherlands.
Department of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Cardiovascular Sciences, The Netherlands.
出版信息
Acute Med. 2023;22(2):61-66. doi: 10.52964/AMJA.0936.
BACKGROUND
Exact benefits of currently recommended close monitoring in intermediate high risk acute pulmonary embolism (PE) patients are unknown.
METHODS
This prospective observational cohort study determined clinical characteristics, and disease course of intermediate high risk acute PE patients in an academic hospital setting . Frequency of hemodynamic deterioration, use of rescue reperfusion therapy and PE related mortality, were outcomes of interest.
RESULTS
Of 98 intermediate high risk PE patients included for analysis, 81 patients (83%) were closely monitored. Two deteriorated hemodynamically and were treated with rescue reperfusion therapy. One patient survived after this.
CONCLUSIONS
In these 98 intermediate high risk PE patients, hemodynamic deterioration occurred in three patients and rescue reperfusion therapy of two closely monitored patients led to survival of one. Underlining the need for better recognition of patients benefitting from and research in the optimal way of close monitoring.
背景
目前建议对中高危急性肺栓塞（PE）患者进行密切监测的确切益处尚不清楚。
方法
本前瞻性观察性队列研究确定了学术医院环境中中高危急性 PE 患者的临床特征和疾病过程。血流动力学恶化的频率、挽救性再灌注治疗的使用和与 PE 相关的死亡率是研究的主要观察终点。
结果
98 例中高危 PE 患者纳入分析，81 例（83%）接受了密切监测。2 例患者血流动力学恶化，接受了挽救性再灌注治疗。其中 1 例患者存活。
结论
在这 98 例中高危 PE 患者中，有 3 例患者出现血流动力学恶化，2 例接受密切监测的患者进行了挽救性再灌注治疗，其中 1 例患者存活。这突出表明需要更好地识别从密切监测中受益的患者，并研究密切监测的最佳方式。
Zotero 插件