Ribeiro-Da-Silva A, Castro-Lopes J M, Coimbra A
Brain Res. 1986 Jul 9;377(2):323-9. doi: 10.1016/0006-8993(86)90875-9.
In the cervical enlargement of the rat spinal cord, fluoride-resistant acid phosphatase (FRAP) occurs in most of the small dark sinuous primary afferent central terminals (CI-terminals) of type I-synaptic glomeruli of lamina II and is lacking in the large light roundish primary afferent CII-terminals of type II-glomeruli. Reactive CI-terminals are heterogeneously distributed across the dorsoventral thickness of lamina II, with maximal frequency in the zone heavily stained for FRAP in light micrographs, which roughly corresponds to the dorsalmost portion of lamina IIi. In the rest of lamina II many CI-terminals do not contain FRAP. Since all CI-terminals appear to originate from unmyelinated, presumably nociceptive, primary afferents, it is proposed that the FRAP-reactive ones arise from the FRAP-containing subpopulation of DRG small cells, while those lacking FRAP, which have a distinct area of termination in the dorsal horn, belong to the peptide-containing subpopulation.
在大鼠脊髓颈膨大处，耐氟酸性磷酸酶（FRAP）存在于II层I型突触小球的大多数小而暗且蜿蜒的初级传入中枢终末（CI终末）中，而在II型小球的大而亮且圆形的初级传入CII终末中则不存在。反应性CI终末在II层的背腹厚度上呈异质性分布，在光镜下FRAP染色较重的区域频率最高，该区域大致对应于IIi层的最背侧部分。在II层的其余部分，许多CI终末不含有FRAP。由于所有CI终末似乎都起源于无髓鞘的、推测为伤害性的初级传入纤维，因此有人提出，具有FRAP反应性的CI终末起源于背根神经节（DRG）小细胞中含FRAP的亚群，而那些缺乏FRAP且在背角有不同终止区域的CI终末则属于含肽亚群。
