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儿童中表现为坏血病的慢性复发性多灶性骨髓炎:一例报告

Chronic Recurrent Multifocal Osteomyelitis Mimicking Scurvy in a Child: A Case Report.

作者信息

Alhalabi Rawan, Nasrallah Basil, Rahman Rizviya, Muad Hussein, Qureshi Assad

机构信息

Department of Pediatrics, American Hospital Dubai, Dubai, ARE.

Department of Orthopaedic Surgery, American Hospital Dubai, Dubai, ARE.

出版信息

Cureus. 2023 May 11;15(5):e38880. doi: 10.7759/cureus.38880. eCollection 2023 May.

DOI:10.7759/cureus.38880
PMID:37313111
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10259692/
Abstract

Scurvy is a rare clinical syndrome resulting from prolonged vitamin C deficiency and is uncommon in the Gulf area. It can present with non-specific symptoms, making diagnosis and treatment challenging. In pediatric patients, symptoms may include weight loss, lethargy, low-grade fever, anemia of varying degrees, easy bruising or bleeding, joint and muscle pain, and poor wound healing. Despite advances in healthcare in many Gulf countries, nutritional deficiencies can still occur in certain populations. Therefore, it is important for pediatricians, orthopedists, rheumatologists, and radiologists to consider scurvy in the evaluation of children with low-grade, multisystemic involvement. We report a case of a six-year-old boy who presented to the emergency department (ED) multiple times with progressive right (RT) leg pain. The clinical picture and imaging findings suggested chronic recurrent multifocal osteomyelitis (CRMO). Despite symptom progression, scurvy was ultimately diagnosed and treatment with vitamin C led to rapid resolution of his symptoms. This case highlights the importance of considering scurvy in the differential diagnosis of children with multisystemic involvement, especially in regions where nutritional deficiencies may be more prevalent.

摘要

坏血病是一种因长期缺乏维生素C而导致的罕见临床综合征,在海湾地区并不常见。它可能表现为非特异性症状,这使得诊断和治疗具有挑战性。在儿科患者中,症状可能包括体重减轻、嗜睡、低热、不同程度的贫血、容易出现瘀伤或出血、关节和肌肉疼痛以及伤口愈合不良。尽管许多海湾国家的医疗保健取得了进展,但某些人群中仍可能出现营养缺乏症。因此,对于儿科医生、骨科医生、风湿病学家和放射科医生来说,在评估有低度、多系统受累的儿童时考虑坏血病很重要。我们报告一例6岁男孩,他多次因右下肢进行性疼痛就诊于急诊科(ED)。临床表现和影像学检查结果提示慢性复发性多灶性骨髓炎(CRMO)。尽管症状持续进展,但最终诊断为坏血病,补充维生素C治疗后其症状迅速缓解。该病例强调了在多系统受累儿童的鉴别诊断中考虑坏血病的重要性,尤其是在营养缺乏可能更为普遍的地区。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9af5/10259692/a6da3e1f4463/cureus-0015-00000038880-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9af5/10259692/a6da3e1f4463/cureus-0015-00000038880-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9af5/10259692/a6da3e1f4463/cureus-0015-00000038880-i01.jpg

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本文引用的文献

1
Chronic Non-infectious Osteomyelitis Mimicking Scurvy as the Presenting Sign of Crohn's Disease: Case Report.以类似坏血病的慢性非感染性骨髓炎为首发表现的克罗恩病:病例报告
Front Pediatr. 2022 Apr 13;10:871993. doi: 10.3389/fped.2022.871993. eCollection 2022.
2
Global Vitamin C Status and Prevalence of Deficiency: A Cause for Concern?全球维生素 C 状况和缺乏症的流行:令人担忧的原因?
Nutrients. 2020 Jul 6;12(7):2008. doi: 10.3390/nu12072008.
3
Vitamin C deficiency mimicking inflammatory bone disease of the hand.维生素 C 缺乏症酷似手部炎性骨病。
Pediatr Rheumatol Online J. 2020 Jun 9;18(1):45. doi: 10.1186/s12969-020-00439-4.
4
Scurvy: A New Old Cause of Skeletal Pain in Young Children.坏血病:幼儿骨骼疼痛的一个新的老病因。
Front Pediatr. 2020 Jan 31;8:8. doi: 10.3389/fped.2020.00008. eCollection 2020.
5
Scurvy Outbreak Among South Sudanese Adolescents and Young Men - Kakuma Refugee Camp, Kenya, 2017-2018.2017-2018 年肯尼亚卡卡马难民营南苏丹青少年和年轻男性中爆发坏血病。
MMWR Morb Mortal Wkly Rep. 2019 Jan 25;68(3):72-75. doi: 10.15585/mmwr.mm6803a4.
6
Chronic recurrent multifocal osteomyelitis: a case report.慢性复发性多灶性骨髓炎:病例报告。
Ital J Pediatr. 2018 Feb 17;44(1):26. doi: 10.1186/s13052-018-0463-3.
7
Scurvy as a mimicker of osteomyelitis in a child with autism spectrum disorder.儿童自闭症谱系障碍并发坏血病,酷似骨髓炎。
Int J Infect Dis. 2018 Apr;69:99-102. doi: 10.1016/j.ijid.2018.02.002. Epub 2018 Feb 6.
8
Chronic Recurrent Multifocal Osteomyelitis (CRMO): Presentation, Pathogenesis, and Treatment.慢性复发性多灶性骨髓炎(CRMO):表现、发病机制与治疗。
Curr Osteoporos Rep. 2017 Dec;15(6):542-554. doi: 10.1007/s11914-017-0405-9.
9
Childhood scurvy: an unusual cause of refusal to walk in a child.儿童坏血病:儿童拒绝行走的罕见原因。
Pediatr Rheumatol Online J. 2015 Jun 11;13:23. doi: 10.1186/s12969-015-0020-1.
10
Scurvy in pediatric age group - A disease often forgotten?小儿年龄组中的坏血病——一种常被遗忘的疾病?
J Clin Orthop Trauma. 2015 Jun;6(2):101-7. doi: 10.1016/j.jcot.2014.12.003. Epub 2015 Jan 5.