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用于资源匮乏地区的低成本集成式新生儿持续气道正压通气血氧饱和度监测设备。

Low-Cost SpO2 Integrated Neonatal CPAP Device for Low Resource Setting.

作者信息

Dawud Ahmed Ali, Abagaro Ahmed Mohammed

机构信息

School of Biomedical Engineering, Jimma Institute of Technology, Jimma University, Jimma, Ethiopia.

出版信息

Med Devices (Auckl). 2023 Jun 8;16:145-156. doi: 10.2147/MDER.S406170. eCollection 2023.

Abstract

INTRODUCTION

More than 60% of preterm births take place in South Asia and sub-Saharan Africa, making prematurity a primary cause of neonatal mortality. Even though continuous positive airway pressure (CPAP) is a popular treatment for respiratory distress syndrome (RDS) and is safe, practicable, and efficient for use in LMICs, it is crucial to ensure that neonates receive the full benefits of the therapy by monitoring their blood oxygen level.

METHODS

A centrifugal fan, power source, control system, and sensors are all included in our design. A centrifugal fan was created to provide air at positive pressure in the range of approximately 4 cmH2O to 20 cmH2O utilizing revolving blades (impeller), a DC motor, and a fixed component. The control unit contains a microcontroller to handle sensor data. The proportional-integral (PI) controller board's external potentiometer is used to set the pressure level.

RESULTS

To ascertain whether the prototype satisfies the design requirements, it was constructed and put through several iterations and testing. The proposed device's prototype was tested for accuracy, affordability, and usability. The centrifugal fan speed measurement was accurate to within 94.5%, while the oxygen concentration sensor reading was accurate to within 98.5%.

CONCLUSION

The design investigates viability of a straightforward, inexpensive, portable SpO2 integrated neonatal CPAP device for use in the delivery room in low-resource countries and to evaluates methods for measuring flows during CPAP treatment by monitoring the level of oxygen in the blood and pressure level delivered by the device using the lowest and safest setting that yields useful results.

摘要

引言

超过60%的早产发生在南亚和撒哈拉以南非洲,这使得早产成为新生儿死亡的主要原因。尽管持续气道正压通气(CPAP)是治疗呼吸窘迫综合征(RDS)的常用方法,并且在低收入和中等收入国家使用安全、可行且有效,但通过监测新生儿的血氧水平来确保他们充分受益于该疗法至关重要。

方法

我们的设计包括一个离心风扇、电源、控制系统和传感器。通过使用旋转叶片(叶轮)、直流电机和固定部件,制造了一个离心风扇,以提供大约4厘米水柱至20厘米水柱范围内的正压空气。控制单元包含一个微控制器来处理传感器数据。比例积分(PI)控制器板的外部电位器用于设置压力水平。

结果

为了确定该原型是否满足设计要求,构建并进行了多次迭代和测试。对所提出设备的原型进行了准确性、可承受性和可用性测试。离心风扇速度测量的准确率在94.5%以内,而氧气浓度传感器读数的准确率在98.5%以内。

结论

该设计研究了一种简单、廉价、便携式的集成血氧饱和度监测功能的新生儿CPAP设备在资源匮乏国家产房使用的可行性,并通过监测血液中的氧气水平和设备以产生有效结果的最低且最安全设置输送的压力水平,评估了CPAP治疗期间测量流量的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0aaa/10259578/b9de0368f7e7/MDER-16-145-g0001.jpg

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